ArticleBMC geriatrics2015
Use of anti-dementia drugs in home care and residential care and associations with neuropsychiatric symptoms: a cross-sectional study.
Article in BMC geriatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- How Nursing Home Nurses Who Care for Residents With Dementia Experience the Moral Distress? A Phenomenography Study.Nursing open · 2025Article
- Gender Disparities in Anti-dementia Medication Use among Older Adults: Health Equity Considerations and Management of Alzheimer's Disease and Related Dementias.Frontiers in pharmacology · 2021Article
- A 24-week double-blind placebo-controlled study of the efficacy and safety of the AMPA modulator S47445 in patients with mild to moderate Alzheimer's disease and depressive symptoms.Alzheimer's & dementia (New York, N. Y.) · 2019Article
- Resourse Use and Disease Couse in dementia - Nursing Home (REDIC-NH), a longitudinal cohort study; design and patient characteristics at admission to Norwegian nursing homes.BMC health services research · 2017Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe number of people with dementia is increasing alongside the aging population, and most of these patients manifest with neuropsychiatric symptoms (NPS). The objective of this study was to investigate anti-dementia drug use and its associations with NPS.
methodsQuestionnaires on demographic information, current drug use, activities of daily living and NPS were sent to all municipal home care producers and to all institutions providing long-term residential care in the South Savo Hospital District, Finland.
resultsThe study population comprised 2821 persons. Their mean age was 81 years and 68% were female. Dementia had been diagnosed in 31% (n = 410) in home care and in 56% (n = 774) in residential care. Anti-dementia drugs were used by 69% of patients with dementia. Hyperactivity symptoms were common in residential care patients (n = 456, 33%), while problems with mood and apathy dominated in home care patients (n = 486, 54%). In multivariate regression analysis, the mood symptoms and apathy subgroup was associated with use of an acetylcholinesterase inhibitor (AChEI) (OR 1.44; 95% Cl 1.03-2.02), memantine (OR 1.77, 95% Cl 1.15-2.72) or their combinations (OR 1.56, 95% Cl 1.03-2.34). Hyperactivity symptoms were associated with combination therapy of this type (OR 2.03, 95% Cl 1.36-2.34).
conclusionsThe use of anti-dementia drugs was common in both care settings. The use of any anti-dementia drug or combination was associated with the mood and apathy subgroup. The hyperactivity subgroup was associated with combination use of memantine and AChEI.
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