ArticleJournal of magnetic resonance imaging : JMRI2016
Selecting the reference image for registration of CEST series.
Article in Journal of magnetic resonance imaging : JMRI, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
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- Molecular-Structural MRI Mismatch for Preoperative Risk Stratification of Pediatric Neuroblastoma.Radiology. Imaging cancer · 2026Article
- APT MRI Signature for Risk Stratification of Pediatric Medulloblastoma.Chemical & biomedical imaging · 2026Article
- Fluid Suppression Techniques Combined With Amide Proton Transfer-Weighted Imaging for the Evaluation of Adult-Type Diffuse Gliomas.Korean journal of radiology · 2026Article
- Magnetic resonance imaging-based assessment of hippocampal glutamate and morphometric changes in preterm infants at term-equivalent age with low birth weight.Pediatric radiology · 2026Article
- Molecular subgrouping of pediatric medulloblastoma by mismatch between molecular and structural MRI.Quantitative imaging in medicine and surgery · 2025Article
- Learning-based motion artifact correction in the Z-spectral domain for chemical exchange saturation transfer MRI.Magnetic resonance in medicine · 2025Article
- Calibration-free whole-brain CEST imaging at 7T with parallel transmit pulse design for saturation homogeneity utilizing universal pulses (PUSHUP).Magnetic resonance in medicine · 2025Article
- Motion and magnetic field inhomogeneity correction techniques for chemical exchange saturation transfer (CEST) MRI: A contemporary review.NMR in biomedicine · 2025Review
- Whole-cerebrum guanidino and amide CEST mapping at 3 T by a 3D stack-of-spirals gradient echo acquisition.Magnetic resonance in medicine · 2024Article
- Multi-pool chemical exchange saturation transfer MRI in glioma grading, molecular subtyping and evaluating tumor proliferation.Journal of neuro-oncology · 2024Article
- Amide proton transfer-weighted imaging and derived radiomics in the classification of adult-type diffuse gliomas.European radiology · 2024Article
- WHO/ISUP grade and pathological T stage of clear cell renal cell carcinoma: value of ZOOMit diffusion kurtosis imaging and chemical exchange saturation transfer imaging.European radiology · 2023Article
- Glutamate alterations in the premature infant brain during different gestational ages with glutamate chemical exchange saturation transfer imaging: a pilot study.European radiology · 2023Article
- Risk stratification of abdominal tumors in children with amide proton transfer imaging.European radiology · 2022Article
- Learning-based analysis of amide proton transfer-weighted MRI to identify true progression in glioma patients.NeuroImage. Clinical · 2022Article
- 3D Amide Proton Transfer Weighted Brain Tumor Imaging With Compressed SENSE: Effects of Different Acceleration Factors.Frontiers in neuroscience · 2022Article
- Differentiation of low- and high-grade pediatric gliomas with amide proton transfer imaging: added value beyond quantitative relaxation times.European radiology · 2021Article
- A Brief History and Future Prospects of CEST MRI in Clinical Non-Brain Tumor Imaging.International journal of molecular sciences · 2021Review
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8 authors.
Funding
Abstract
backgroundTo compare different reference images selected for registration among chemical exchange saturation transfer (CEST) series. MATERIALS AND
methodsFive normal volunteers and eight brain tumor patients were studied on a 3 Tesla scanner. Image registration was performed by choosing each of the acquired CEST saturation or unsaturation dynamic images as the reference. CEST images at 3.5 ppm (amide proton transfer, APT) were computed for each motion-corrected data set after main magnetic field inhomogeneity correction. A uniformity index was defined to quantify the efficacy of image registration using different reference images. Joint histograms and the structural similarity index (SSIM) were used to analyze the intrinsic image similarity between various dynamic images.
resultsImage registration increased the average uniformity index by 18% if the 3.5 ppm saturated image was selected as the reference image. However, registering to the unsaturated dynamic image reduced the uniformity index by 13% on average. The joint histogram analysis showed that the saturated dynamic images were highly similar (SSIM = 0.89 ± 0.01), and were considerably different from the unsaturated dynamic image (SSIM = 0.58 ± 0.03).
conclusionThe selection of the 3.5 ppm dynamic image as the reference image generated the highest uniformity index for APT imaging though other saturated images were equally suited as reference images.
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