ArticleThe British journal of radiology2015
Quantified ultrasound elastography in the assessment of cutaneous carcinoma.
Article in The British journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 40 citations in OpenAlex.
- Review of Non-Invasive Imaging Technologies for Cutaneous Melanoma.Biosensors · 2025Review
- Asynchronous, semi-reverberant elastography.Optica · 2024Article
- Diagnostic accuracy of high-frequency ultrasound for cutaneous neoplasms: a narrative review of the literature.Archives of dermatological research · 2024Review
- Practical approach to ultrasound of soft tissue tumors and the added value of MRI: how I do it.Journal of ultrasonography · 2023Article
- High-Frequency Ultrasound in Diagnosis and Treatment of Non-Melanoma Skin Cancer in the Head and Neck Region.Diagnostics (Basel, Switzerland) · 2023Article
- Role of shear wave elastography ultrasound in patients with systemic sclerosis.Journal of ultrasound · 2022Article
- High-frequency ultrasound for differentiation between high-risk basal cell carcinoma and cutaneous squamous cell carcinoma.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2022Article
- Differentiation of benign and malignant superficial soft tissue lesions using real-time strain elastographyTurkish journal of medical sciences · 2021Article
- Is Computer-Assisted Tissue Image Analysis the Future in Minimally Invasive Surgery? A Review on the Current Status of Its Applications.Journal of clinical medicine · 2021Review
- Article
- Use of imaging techniques for melanocytic naevi and basal cell carcinoma in integrative analysis (Review).Experimental and therapeutic medicine · 2020Review
- Ultrasonographic elastography in the evaluation of normal and pathological skin - a review.Postepy dermatologii i alergologii · 2019Review
- Elastography reference values of facial skin elasticity.Postepy dermatologii i alergologii · 2019Article
- Ultrasound and Infrared-Based Imaging Modalities for Diagnosis and Management of Cutaneous Diseases.Frontiers in medicine · 2018Review
- Measurement of shear wave speed dispersion in the placenta by transient elastography: A preliminary ex vivo study.PloS one · 2018Article
- The validity and reliability of using ultrasound elastography to measure cutaneous stiffness, a systematic review.International journal of burns and trauma · 2017Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the feasibility of high-frequency ultrasound and ultrasound elastography (USE) in discriminating benign from malignant skin lesions in a prospective cohort study and to introduce the use of a "strain ratio" for evaluation of skin lesions.
methodsA commercial ultrasound system with a 14-MHz transducer was used to visualize skin lesions requiring biopsy on clinical evaluation. Anatomic ultrasound and USE imaging of the skin lesions was performed using 2- to 4-mm gel stand-off pads. A region of interest was manually selected over the area of each lesion with the lowest strain. The concept of a strain ratio of the compressibility of the normal skin at the corresponding layer to that of the least compressible region of a lesion in question was created and applied. This ratio was subsequently correlated with blind histopathological evaluation for malignancy.
results55 patients were included in the study with a total of 67 lesions evaluated. 29 lesions were malignant and 38 benign. All malignant lesions had strain ratios ≥3.9. All benign lesions had strain ratios ≤3.0. A diagnostic value between 3.0 and 3.9 would result in 100% sensitivity and specificity in the characterization of these lesions as malignant.
conclusionThis pilot study demonstrated that USE plus strain ratio appears to be a promising modality in providing diagnostic determination between cancerous and benign primary solitary skin lesions prior to biopsy. ADVANCES IN KNOWLEDGE: This is the first reported study applying an original mathematical elastographic ratio, or strain ratio, to evaluate primary solitary skin lesions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.