Evidence map›Paper›PMID 26266269›Full record

ReviewJournal of immunology research2015

Microbiome and Asthma: What Have Experimental Models Already Taught Us?

R Bonamichi-Santos, M V Aun, R C Agondi, J Kalil, P Giavina-Bianchi

Abstract readReview
In one paragraph

Review in Journal of immunology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Animal models of asthma: utility and limitations.Journal of asthma and allergy · 2017
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R Bonamichi-SantosClinical Immunology and Allergy Division, University of São Paulo School of Medicine, 01454-010 São Paulo, SP, Brazil.
M V AunClinical Immunology and Allergy Division, University of São Paulo School of Medicine, 01454-010 São Paulo, SP, Brazil.
R C AgondiClinical Immunology and Allergy Division, University of São Paulo School of Medicine, 01454-010 São Paulo, SP, Brazil.
J KalilClinical Immunology and Allergy Division, University of São Paulo School of Medicine, 01454-010 São Paulo, SP, Brazil.
P Giavina-BianchiClinical Immunology and Allergy Division, University of São Paulo School of Medicine, 01454-010 São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a chronic inflammatory disease that imposes a substantial burden on patients, their families, and the community. Although many aspects of the pathogenesis of classical allergic asthma are well known by the scientific community, other points are not yet understood. Experimental asthma models, particularly murine models, have been used for over 100 years in order to better understand the immunopathology of asthma. It has been shown that human microbiome is an important component in the development of the immune system. Furthermore, the occurrence of many inflammatory diseases is influenced by the presence of microbes. Again, experimental models of asthma have helped researchers to understand the relationship between the microbiome and respiratory inflammation. In this review, we discuss the evolution of murine models of asthma and approach the major studies involving the microbiome and asthma.

Indexed as

MicrobiotaAllergensAnimalsAsthmaDisease Models, AnimalEnvironmental MicrobiologyGastrointestinal MicrobiomeHumansMiceResearchRespiratory MucosaAllergens

Identifiers

PMID26266269
PMCPMC4525458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.