Evidence map›Paper›PMID 26265715›Full record

ReviewClinical journal of the American Society of Nephrology : CJASN2015

Chronic Renal Insufficiency Cohort Study (CRIC): Overview and Summary of Selected Findings.

Matthew Denker, Suzanne Boyle, Amanda H Anderson, Lawrence J Appel, Jing Chen, Jeffrey C Fink, John Flack, Alan S Go, Edward Horwitz, Chi-Yuan Hsu and 9 more

Abstract readReview
In one paragraph

Review in Clinical journal of the American Society of Nephrology : CJASN, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Contrastive Latent Functional Model.Statistics in biosciences · 2026
    Article
  9. Article
  10. Family History of Kidney Failure, APOL1 Risk Variants, Social Determinants of Health, and Risk of CKD Progression: Findings From the CRIC Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026
    Observational
  11. Article
  12. Diabetes Genetic Clusters and Clinical Outcomes in the Chronic Renal Insufficiency Cohort.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  13. Review
  14. Review
  15. Association of Obesity and Body Composition and Hospitalization Risk with Infection in the CRIC Study.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Matthew DenkerDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Suzanne BoyleDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Amanda H AndersonDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Lawrence J AppelDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Jing ChenDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Jeffrey C FinkDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
John FlackDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Alan S GoDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Edward HorwitzDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Chi-Yuan HsuDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
John W KusekDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
James P LashDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Sankar NavaneethanDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Akinlolu O OjoDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Mahboob RahmanDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Susan P SteigerwaltDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Raymond R TownsendDue to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Harold I FeldmanDue to the number of contributing authors, the affiliations are provided in the Supplemental Material. hfeldman@mail.med.upenn.edu.
Chronic Renal Insufficiency Cohort Study Investigators

Funding

Scientific and Data Coordinating Center(SDCC) for the P*U01DK060990 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI FELDMAN, HAROLD I · 2001 to 2017
$50.1M
Study of the Care and Outcomes of REnal InsufficiencyU01DK060902 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI GO, ALAN S · 2001 to 2025
$19.5M
Limited Competition for the Continuation of the Chronic Renal Insufficiency CohorU01DK061021 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI RAHMAN, MAHBOOB · 2001 to 2025
$17.3M
Translational Research in Hypertension and Renal BiologyP30GM103337 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI HAMM, L LEE · 2012 to 2016
$5.8M
CLINICAL RESEARCH TRAINING IN KIDNEY DISEASET32DK007785 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI FELDMAN, HAROLD I · 2000 to 2019
$3.9M
A pilot trial of an intervention to support initial type 2 diabetes selfmanagement among younger adults with children.R01DK139225 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Anjali Gopalan · 2025 to 2026
$649k
NIDDK NIH HHS R01 DK139225NIDDK NIH HHS U01 DK060902NIDDK NIH HHS U01 DK060990NIDDK NIH HHS U01 DK061021NIGMS NIH HHS P30 GM103337
6 · The paper itself

Abstract

The Chronic Renal Insufficiency Cohort (CRIC) Study is a United States multicenter, prospective study of racially and ethnically diverse patients with CKD. Although the original aims of the study were to identify novel predictors of CKD progression and to elucidate the risk and manifestations of cardiovascular disease among nearly 4000 individuals with CKD, the CRIC Study has evolved into a national resource for investigation of a broad spectrum of CKD-related topics. The study has produced >90 published scientific articles, promoted many young investigative careers in nephrology, and fostered international collaborations focused on understanding the global burden of CKD. The third phase of the CRIC Study will complete enrollment of 1500 additional study participants in 2015 and is designed to answer questions regarding morbidity and mortality in mild-to-moderate CKD and to assess the burden of CKD in older persons. This review highlights some of the salient findings of the CRIC Study in the areas of race and ethnicity, CKD progression, CKD and cognition, and cardiovascular disease outcomes; it also outlines the ongoing and forthcoming opportunities for the global nephrology community to enhance its understanding of CKD and related complications through the study.

Indexed as

Renal Insufficiency, ChronicCardiovascular DiseasesCohort StudiesDisease ProgressionHumansRacial Groupschronic kidney diseasechronic renal insufficiencycohort study

Identifiers

PMID26265715
PMCPMC4633788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.