Observational studyJournal of gastroenterology2016
Body mass index association with functional gastrointestinal disorders: differences between genders. Results from a study in a tertiary center.
Observational study in Journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Examining the Association Between Overweight, Obesity, and Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- Impact of body mass index on the efficacy of acupuncture treatment of postprandial distress syndrome: secondary analysis of a randomized clinical trial.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026Trial
- Associations of Functional Dyspepsia with Eating Behaviors and Stress-Coping Styles Among Japanese University Students.Nutrients · 2026Article
- Exploring population and sex-specific disease trajectories for multimorbidities among individuals with overweight or obesity: A retrospective cohort study in UK biobank.Diabetes, obesity & metabolism · 2025Article
- Association of metabolomic aging acceleration and body mass index phenotypes with mortality and obesity-related morbidities.Aging cell · 2025Article
- Prospective Monitoring of Small Intestinal Bacterial Overgrowth After Gastric Bypass: Clinical, Biological, and Gas Chromatographic Aspects.Obesity surgery · 2024Article
- Prevalence and predictors of functional gastrointestinal disorder among the undergraduate students of Bangladesh.PloS one · 2024Article
- Assesment of functional gastrointestinal diseases in obese children.European journal of pediatrics · 2023Article
- Association of vitamin D and functional dyspepsia: a case-control study.Annals of medicine and surgery (2012) · 2023Article
- Investigation of Eating Habits in Patients with Functional Dyspepsia.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022Article
- Association Between Body Mass Index and Functional Dyspepsia in Young Japanese People.Journal of neurogastroenterology and motility · 2022Article
- 'Persistent throat symptoms' versus 'laryngopharyngeal reflux': a cross-sectional study refining the clinical condition.BMJ open gastroenterology · 2022Article
- Discovery of Drug Candidates for Specific Human Disease Based on Natural Products of Gut Microbes.Frontiers in microbiology · 2022Article
- The association of body mass index with functional dyspepsia is independent of psychological morbidity: A cross-sectional study.PloS one · 2021Article
- Influence of Age and Body Mass Index on Total and Segmental Colonic Transit Times in Constipated Subjects.Journal of neurogastroenterology and motility · 2019Article
- Prevalence and predictors of irritable bowel syndrome in patients with morbid obesity: a cross-sectional study.BMC obesity · 2017Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity is considered as a risk factor for many functional gastrointestinal disorders. The aim of the study was to evaluate if functional digestive disorders are associated with specific body mass index groups and gender.
methodsA total of 1074 patients (50.3 ± 16.5 years, 67 % females) filled out a standard Rome III questionnaire (79 % acceptance rate). The patients were assigned to five groups according to their body mass index: underweight (6 %), normal (49 %), overweight (28 %), obese (12 %), and morbidly obese (5 %). Data analysis was performed using multinomial logistic regression; subjects with the normal weight were the reference group.
resultsPatients presented specific demographic and clinical characteristics according to the weight groups. Underweight patients were younger (p < 0.001), and presented a female predominance (p = 0.006), dysphagia (p = 0.013) and soiling (p = 0.021). Overweight patients were older (p = 0.001), and reported more frequently globus (p = 0.001), regurgitation (p = 0.004), postprandial distress syndrome (p = 0.009). Obese patients reported more frequently regurgitation (p < 0.001). Morbid obese patients reported dyspepsia (p = 0.046). In patients, the odds of regurgitation increased with body mass index from underweight to obesity, but not when compared to morbid obesity. The probability of globus and regurgitation increased with body mass index and presented a steeper increase in females.
conclusionsIn patients with functional gastrointestinal disorders, globus and regurgitation are associated with body mass index, mainly in female patients.
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