Evidence map›Paper›PMID 26265201›Full record

Trial reportCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2015

Impact of Risk Assessment and Tailored versus Nontailored Risk Information on Colorectal Cancer Testing in Primary Care: A Randomized Controlled Trial.

Celette Sugg Skinner, Ethan A Halm, Wendy Pechero Bishop, Chul Ahn, Samir Gupta, David Farrell, Jay Morrow, Manjula Julka, Katharine McCallister, Joanne M Sanders and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Personalizing cancer risk: a systematic review of risk communication strategies.Journal of cancer research and clinical oncology · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
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  8. Review
  9. Article
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  12. Outcomes associated with use of thePreventive medicine reports · 2019
    Article
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  15. Screening for colorectal cancer: the role of the primary care physician.European journal of gastroenterology & hepatology · 2017
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Celette Sugg SkinnerSimmons Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas. Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas. celette.skinner@utsouthwestern.edu.
Ethan A HalmSimmons Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas. Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas. Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas.
Wendy Pechero BishopDepartment of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
Chul AhnSimmons Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas. Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
Samir GuptaVeterans Affairs San Diego Healthcare System, Division of Gastroenterology, Department of Internal Medicine, and the Moores Cancer Center, University of California San Diego, San Diego, California.
David FarrellPeople Designs, Durham, North Carolina.
Jay MorrowDepartment of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas.
Manjula JulkaDepartment of Family and Community Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas.
Katharine McCallisterDepartment of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
Joanne M SandersDepartment of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
Emily MarksDepartment of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
Susan M RawlIndiana University School of Nursing and Simon Cancer Center, Indianapolis, Indiana.

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
Facilitating Risk-Appropriate Colorectal Cancer TestingR01CA122330 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI SKINNER, CELETTE SUGG · 2007 to 2010
$1.7M
NCATS NIH HHS UL1 TR001105NCI NIH HHS R01 CA122330
6 · The paper itself

Abstract

backgroundColorectal cancer screening is effective but underused. Guidelines for which tests are recommended and at what intervals depend on specific risks. We developed a tablet-based Cancer Risk Intake System (CRIS) that asks questions about risk prior to appointments and generates tailored printouts for patients and physicians summarizing and matching risk factors with guideline-based recommendations.

methodsRandomized controlled trial among patients who: (i) used CRIS and they and their physicians received tailored printouts; (ii) used CRIS to answer questions but received standard information about cancer screening while their physicians received a standard electronic chart prompt indicating they were age-eligible but not currently adherent for colorectal cancer screening; or (iii) comprised a no-contact group that neither used CRIS nor received any information while their physicians received the standard prompt. Participation in testing was assessed via electronic medical record at 12 months.

resultsParticipation in any colorectal cancer testing was three times higher for those who used the CRIS and received any printed materials, compared with no-contact controls (47% vs. 16%; P < 0.0001). Among CRIS users ages 50 and older, participation in any testing was higher in the tailored group (53% vs. 44%, P = 0.023).

conclusionUse of CRIS and receipt of any information facilitated participation in testing. There was more testing participation in the CRIS-tailored than nontailored group. IMPACT: Asking patients questions about their specific risk factors and giving them and their providers information just prior to an appointment may increase participation in colorectal cancer testing. Tailoring the information has some added benefit.

Indexed as

Electronic Health RecordsRisk AssessmentColonoscopyColorectal NeoplasmsEarly Detection of CancerFemaleHumansMaleMass ScreeningMiddle AgedMorbidityOccult BloodPatient CompliancePrimary Health CareRisk FactorsUnited States

Identifiers

PMID26265201
PMCPMC4592452

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.