ArticleCellular and molecular life sciences : CMLS2015
Identification and functional analysis of olfactory receptor family reveal unusual characteristics of the olfactory system in the migratory locust.
Article in Cellular and molecular life sciences : CMLS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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52 citing papers in PubMed, 98 citations in OpenAlex.
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- Anatomical Investigation Reveals a Second Olfactory System in Locusts.The Journal of comparative neurology · 2026Article
- A Comprehensive Molecular and Evolutionary Characterization of Chemosensory-Related Genes inAnimals : an open access journal from MDPI · 2026Article
- Genome-Wide Identification and Characterization of Chemosensory Gene Families in the MayflyGenes · 2026Article
- Comparative Analysis Reveals the Adaptive Evolution of Olfactory System in the Swamp Eel (Ecology and evolution · 2026Article
- Article
- Expanding the sensory horizon: chemosensory receptors beyond traditional olfactory and taste organs in insects.Science China. Life sciences · 2026Review
- The Integrative Imperatives of Locust Phase Polyphenism Research: A Bibliometric Analysis.Integrative organismal biology (Oxford, England) · 2026Review
- Transcriptomic Analysis and Comparative Analysis of Gene Families Related to Environmental Adaptation in Two Grylloblattodea Species:Ecology and evolution · 2025Article
- Probing the optimal architecture and molecular mechanism of insect odorant receptor heteromeric channels.Communications biology · 2025Article
- Characterization of chemosensory genes in the subterranean pest Gryllotalpa Orientalis based on genome assembly and transcriptome comparison.BMC genomics · 2025Article
- Dibutyl phthalate released by solitary female locusts mediates sexual communication at low density.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genome-Wide Identification of the Odorant Receptor Gene Family and Revealing Key Genes Involved in Sexual Communication inInternational journal of molecular sciences · 2023Article
- The specific expression patterns of sensory neuron membrane proteins are retained throughout the development of the desert locustCurrent research in insect science · 2023Article
- Identification and analysis of odorant receptors expressed in the two main olfactory organs, antennae and palps, of Schistocerca americana.Scientific reports · 2022Article
- Genome-wide identification and expression profiling of odorant receptor genes in the malaria vector Anopheles sinensis.Parasites & vectors · 2022Article
- Identification and Tissue Expression Profiles of Odorant Receptor Genes in the Green Peach AphidInsects · 2022Article
- Developmental and evolutionary constraints on olfactory circuit selection.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Chemical Ecology and Olfaction in Short-Horned Grasshoppers (Orthoptera: Acrididae).Journal of chemical ecology · 2022Review
- Transcriptome analysis ofFrontiers in physiology · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Locusts represent the excellent model of insect olfaction because the animals are equipped with an unusual olfactory system and display remarkable density-dependent olfactory plasticity. However, information regarding receptor molecules involved in the olfactory perception of locusts is very limited. On the basis of genome sequence and antennal transcriptome of the migratory locust, we conduct the identification and functional analysis of two olfactory receptor families: odorant receptors (ORs) and ionotropic receptors (IRs). In the migratory locust, there is an expansion of OR family (142 ORs) while distinctly lower number of IR genes (32 IRs) compared to the repertoires of other insects. The number of the locust OR genes is much less than that of glomeruli in antennal lobe, challenging the general principle of the "one glomerulus-one receptor" observed in other insects. Most OR genes are found in tandem arrays, forming two large lineage-specific subfamilies in the phylogenetic tree. The "divergent IR" subfamily displays a significant contraction, and most of the IRs belong to the "antennal IR" subfamily in the locust. Most ORs/IRs have olfactory-specific expression while some broadly- or internal-expressed members are also found. Differing from holometabolous insects, the migratory locust contains very similar expression profiles of ORs/IRs between nymph and adult stages. RNA interference and behavioral assays indicate that an OR-based signaling pathway, not IR-based, mediates the attraction of locusts to aggregation pheromones. These discoveries provide insights into the unusual olfactory system of locusts and enhance our understanding of the evolution of insect olfaction.
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