ArticleJournal of neurovirology2016
Intrinsic network connectivity abnormalities in HIV-infected individuals over age 60.
Article in Journal of neurovirology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Reversible large-scale network disruption correlates with neurocognitive improvement in HIV-associated minor neurocognitive disorder with combined anti-retroviral therapy intensification: a prospective longitudinal resting-state functional magnetic resonance imaging study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Resting state network connectivity alterations in HIV: Parallels with aging.Human brain mapping · 2023Article
- The default mode network is affected in the early stage of simian immunodeficiency virus infection: a longitudinal study.Neural regeneration research · 2023Article
- Cortico-striatal networking deficits associated with advanced HIV disease and cocaine use.Journal of neurovirology · 2023Article
- Neurofunctional characteristics of executive control in older people with HIV infection: a comparison with Parkinson's disease.Brain imaging and behavior · 2022Article
- Prior Methamphetamine Use Disorder History Does Not Impair Interoceptive Processing of Soft Touch in HIV Infection.Viruses · 2021Article
- Human immunodeficiency virus-related decreases in corpus callosal integrity and corresponding increases in functional connectivity.Human brain mapping · 2021Article
- Alterations of Brain Signal Oscillations in Older Individuals with HIV Infection and Parkinson's Disease.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021Article
- A comprehensive data-driven analysis framework for detecting impairments in brain function networks with resting state fMRI in HIV-infected individuals on cART.Journal of neurovirology · 2021Article
- Synergistic effects of HIV and marijuana use on functional brain network organization.Progress in neuro-psychopharmacology & biological psychiatry · 2021Article
- Deep Phenotyping of HIV Neurocognitive Complications Among Individuals Residing in High-Income Countries.Current topics in behavioral neurosciences · 2021Article
- Mindfulness-based stress reduction for HIV-associated neurocognitive disorder: Rationale and protocol for a randomized controlled trial in older adults.Contemporary clinical trials · 2020Article
- Detecting cognitive impairment in HIV-infected individuals using mutual connectivity analysis of resting state functional MRI.Journal of neurovirology · 2020Article
- Diagnostic and prognostic biomarkers for HAND.Journal of neurovirology · 2019Review
- Low-frequency fluctuation characteristics in rhesus macaques with SIV infection: a resting-state fMRI study.Journal of neurovirology · 2019Article
- Effects of early HIV infection and combination antiretroviral therapy on intrinsic brain activity: a cross-sectional resting-state fMRI study.Neuropsychiatric disease and treatment · 2019Article
- Resting-state connectivity and spontaneous activity of ventromedial prefrontal cortex predict depressive symptomology and peripheral inflammation in HIV.Journal of neurovirology · 2018Article
- Altered cerebro-cerebellum resting-state functional connectivity in HIV-infected male patients.Journal of neurovirology · 2018Article
- Structural and functional brain imaging in acute HIV.NeuroImage. Clinical · 2018Article
- Resting-state functional magnetic resonance imaging in clade C HIV: within-group association with neurocognitive function.Journal of neurovirology · 2017Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Individuals infected with HIV are living longer due to effective treatment with combination antiretroviral therapy (cART). Despite these advances, HIV-associated neurocognitive disorders (HAND) remain prevalent. In this study, we analyzed resting state functional connectivity (rs-fc) data from HIV-infected and matched HIV-uninfected adults aged 60 years and older to determine associations between HIV status, neuropsychological performance, and clinical variables. HIV-infected participants with detectable plasma HIV RNA exhibited decreased rs-fc within the salience (SAL) network compared to HIV-infected participants with suppressed plasma HIV RNA. We did not identify differences in rs-fc within HIV-infected individuals by HAND status. Our analysis identifies focal deficits in the SAL network that may be mitigated with suppression of plasma virus. However, these findings suggest that rs-fc may not be sensitive as a marker of HAND among individuals with suppressed plasma viral loads.
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