ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2015
Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers: a pilot study.
Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Electronic Cigarette Use and Blood Pressure Endpoints: a Systematic Review.Current hypertension reports · 2020Pooled it
- Overview of Electronic Nicotine Delivery Systems: A Systematic Review.American journal of preventive medicine · 2017Pooled it
- Reduced vascular function, ventilatory efficiency and exercise capacity in young adult electronic cigarette users.ERJ open research · 2026Article
- Review
- E-Cigarette Smoke Exposure Elevates Renal MR Expression and Induces BP Elevation.Hypertension (Dallas, Tex. : 1979) · 2025Article
- Cardiovascular Health Effects and Synthetic Cooling Agents in E-Cigarettes Labeled as "Clear" Marketed in Massachusetts After the Tobacco Product Flavoring Ban.Journal of the American Heart Association · 2025Article
- Direct health implications of e-cigarette use: a systematic scoping review with evidence assessment.Frontiers in public health · 2024Article
- E-Cigarette Toxicology.Annual review of pharmacology and toxicology · 2022Review
- Well-being and harm reduction, the consolidated reality of electronic cigarettes ten years later from this emerging phenomenon: A narrative review.Health psychology research · 2020Article
- Acute effects of electronic cigarette smoking on ventricular repolarization in adults.African health sciences · 2020Article
- Short-term e-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic NADPH oxidase (NOX-2).European heart journal · 2020Article
- Tobacco smoking, related harm and motivation to quit smoking in people with schizophrenia spectrum disorders.Health psychology research · 2020Article
- Sociodemographic Correlates of Electronic Nicotine Delivery Systems (ENDS) Use in the United States, 2016-2017.American journal of public health · 2019Article
- Vape Gods and Judaism-E-cigarettes and Jewish Law.Rambam Maimonides medical journal · 2019Review
- Cardiovascular injury induced by tobacco products: assessment of risk factors and biomarkers of harm. A Tobacco Centers of Regulatory Science compilation.American journal of physiology. Heart and circulatory physiology · 2019Review
- Nicotine and the renin-angiotensin system.American journal of physiology. Regulatory, integrative and comparative physiology · 2018Review
- Chronic exposure to electronic cigarettes results in impaired cardiovascular function in mice.Journal of applied physiology (Bethesda, Md. : 1985) · 2018Article
- Effect of nicotine on placental ischemia-induced complement activation and hypertension in the rat.Journal of immunotoxicology · 2017Article
- Acute effects of short term use of ecigarettes on Airways Physiology and Respiratory Symptoms in Smokers with and without Airway Obstructive Diseases and in Healthy non smokers.Tobacco prevention & cessation · 2017Article
- Effects of Acute Vaporized Nicotine in Non-Tobacco Users at Rest and during Exercise.International journal of exercise scienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeElectronic cigarettes are growing in popularity, but the physiological consequences of vaporized nicotine are unknown.
methodsTwenty healthy non-smokers inhaled vaporized nicotine and placebo (randomized).
resultsNicotine inhalation was associated with higher arterial pressures in the seated position, and increased arterial pressures in the head-up positions with no other effects on autonomic control.
conclusionsOur results show that vaporized nicotine inhalation is not innocuous. Longitudinal studies in otherwise healthy non-smokers should be conducted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.