Evidence map›Paper›PMID 26264790›Full record

ReviewPediatric nephrology (Berlin, Germany)2016

How does your kidney smell? Emerging roles for olfactory receptors in renal function.

Blythe D Shepard, Jennifer L Pluznick

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. A guide to uraemic toxicity.Nature reviews. Nephrology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Olfactory receptors contribute to progression of kidney fibrosis.NPJ systems biology and applications · 2022
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. The analysis of a time-course transcriptome profile by systems biology approaches reveals key molecular processes in acute kidney injury.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019
    Article
  19. A longitudinal study of altered taste and smell perception and change in blood pressure.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Blythe D ShepardJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Jennifer L PluznickJohns Hopkins University School of Medicine, Baltimore, MD, USA. jpluznick@jhmi.edu.ORCID http://orcid.org/0000-0003-3621-2665
Johns Hopkins University · US

Funding

Renal Olfactory Receptor 1393: Ligands, Localization and FunctionF32DK096780 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SHEPARD, BLYTHE D · 2012 to 2014
$156k
NIDDK NIH HHS F32 DK096780NIDDK NIH HHS F32-DK096780
6 · The paper itself

Abstract

Olfactory receptors (ORs) are chemosensors that are responsible for one's sense of smell. In addition to this specialized role in the nose, recent evidence suggests that ORs are also found in a variety of additional tissues including the kidney. As this list of renal ORs continues to expand, it is becoming clear that they play important roles in renal and whole-body physiology, including a novel role in blood pressure regulation. In this review, we highlight important considerations that are crucial when studying ORs and present the current literature on renal ORs and their emerging relevance in maintaining renal function.

Indexed as

Signal TransductionSmellAnimalsBlood PressureHumansKidneyLigandsMechanotransduction, CellularReceptors, OdorantRenal CirculationLigandsReceptors, OdorantAdenylate cyclase 3Blood pressureKidneyLigandOdorant receptorOlfactory receptors

Identifiers

PMID26264790
PMCPMC4752438
OpenAlexW1161630335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.