Evidence map›Paper›PMID 26264475›Full record

ArticleInternational urogynecology journal2016

Preoperative vaginal estrogen and midurethral sling exposure: a retrospective cohort study.

Lauren A Cadish, Elizabeth H West, Jessica Sisto, Teresa Longoria, Judith D Bebchuk, Emily L Whitcomb

Abstract read
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In one paragraph

Article in International urogynecology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lauren A CadishDepartment of Obstetrics and Gynecology, University of California Irvine Medical Center, 101 The City Drive, Building 56, Suite 800, Orange, CA, 92868, USA. lcadish@uci.edu.
Elizabeth H WestDepartment of Obstetrics and Gynecology, University of California Irvine Medical Center, 101 The City Drive, Building 56, Suite 800, Orange, CA, 92868, USA.
Jessica SistoDepartment of Obstetrics and Gynecology, University of California Irvine Medical Center, 101 The City Drive, Building 56, Suite 800, Orange, CA, 92868, USA.
Teresa LongoriaDepartment of Obstetrics and Gynecology, University of California Irvine Medical Center, 101 The City Drive, Building 56, Suite 800, Orange, CA, 92868, USA.
Judith D BebchukDepartment of Research and Evaluation, Southern California Permanente Medical Group, Pasadena, CA, USA.
Emily L WhitcombDepartment of Obstetrics and Gynecology, Southern California Permanente Medical Group, Irvine Medical Center, Irvine, CA, USA. Emily.L.Whitcomb@kp.org.
University of California, Irvine Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisWe evaluated whether the use of estrogen vaginally prior to synthetic midurethral sling insertion mediates the risk of mesh exposure. A secondary aim was to evaluate other factors that may be associated with mesh exposure.

methodsWe performed a retrospective cohort study of patients undergoing midurethral sling insertion from January to December 2010 within the Southern California Permanente Medical Group. Women who used estrogen vaginally prior to surgery were classified as those who filled a prescription between 1 and 45 days before surgery or whose medical records indicated its use at the time of preoperative evaluation. Logistic regression analysis was used to calculate odds ratios (OR) and 95 % confidence intervals (CI) for factors associated with mesh exposure while controlling for confounding variables.

resultsA total of 1544 patients met inclusion criteria, of whom 248 (16.1 %) used estrogen vaginally prior to surgery. Mean age was 53.7 years (range 27-89). Thirty-seven (2.4 %) women were diagnosed with mesh exposure, of whom 19 underwent surgical reoperation. In multivariate logistic regression analysis, preoperative use of estrogen vaginally was not associated with the risk of mesh exposure (OR 0.79, CI 0.26-2.38, p = 0.67). Age, body mass index, menopausal status, use of hormone replacement therapy, smoking status, and diabetes were not associated with risk of mesh exposure.

conclusionsPreoperative use of estrogen vaginally did not appear to mediate the risk of mesh exposure following midurethral sling placement in this cohort.

Indexed as

Administration, IntravaginalAdultAgedAged, 80 and overEstrogensFemaleHumansMiddle AgedPostoperative ComplicationsPreoperative CareRetrospective StudiesSuburethral SlingsEstrogensEstrogenMesh exposureMidurethral sling

Identifiers

PMID26264475
OpenAlexW1194320063

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.