Trial reportInternational journal of cancer2016
Increased breast cancer screening and downstaging in Colombian women: A randomized trial of opportunistic breast-screening.
Trial report in International journal of cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- A systematic review of public health interventions to address breast cancer inequalities in low- and middle-income countries.Systematic reviews · 2024Pooled it
- Pooled it
- Economic benefit of expanding mammography screening for breast cancer in Colombia: A cost modelling analysis.Public health in practice (Oxford, England) · 2026Article
- Challenges and facilitators in pathways to cancer diagnosis in Southern Africa: a qualitative study.BMJ open · 2025Article
- Three-year survival of breast cancer patients attending a one-stop breast care clinic nested within a primary care health facility in sub-Saharan Africa-Zambia.International journal of cancer · 2024Article
- Cross-sector co-creation of a community-based physical activity program for breast cancer survivors in Colombia.Health promotion international · 2022Article
- Factors Associated with Time to Progression and Overall Survival in Patients with De Novo Metastatic Breast Cancer: A Colombian Cohort.The oncologist · 2022Observational
- The impact of the Covid-19 pandemic on breast cancer early detection and screening.Preventive medicine · 2021Article
- Screen-detected breast cancer is associated with better prognosis and survival compared to self-detected/symptomatic cases in a Chilean cohort of female patients.Breast cancer research and treatment · 2021Article
- The Effect of Educational Intervention Based on the Theory of Planned Behavior on Mammography Screening in Iranian Women.Journal of cancer education : the official journal of the American Association for Cancer Education · 2020Article
- Breast Cancer Knowledge Assessment of Health Workers in Ibadan, Southwest Nigeria.JCO global oncology · 2020Article
- Prevention of cervical and breast cancer mortality in low- and middle-income countries: a window of opportunity.International journal of women's health · 2019Article
- Research Needs for Implementing Cancer Prevention and Early Detection in Developing Countries: From Scientists' to Implementers' Perspectives.BioMed research international · 2019Review
- Sentinel Lymph Node Biopsy Pathology and 2-Year Postsurgical Recurrence of Breast Cancer in Kenyan Women.Journal of global oncology · 2018Article
- Early detection and treatment strategies for breast cancer in low-income and upper middle-income countries: a modelling study.The Lancet. Global health · 2018Article
- Health Damaged Context: Barriers to Breast Cancer Screening from Viewpoint of Iranian Health VolunteersAsian Pacific journal of cancer prevention : APJCP · 2018Article
- Breast Cancer in Men: Clinical and Pathological Analysis of 817 Cases.American journal of men's healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 4 countries.
Funding
Abstract
The lack of breast cancer screening in low and middle-income countries results in later stage diagnosis and worsened outcomes for women. A cluster randomized trial was performed in Bogotá, Colombia between 2008 and 2012 to evaluate effects of opportunistic breast cancer screening. Thirteen clinics were randomized to an intervention arm and 13 to a control arm. Physicians in intervention clinics were instructed to perform clinical breast examination on all women aged 50-69 years attending clinics for non-breast health issues, and then refer them for mammographic screening. Physicians in control clinics were not explicitly instructed to perform breast screening or mammography referrals, but could do so if they thought it indicated ("usual care"). Women were followed for 2-years postrandomization. 7,436 women were enrolled and 7,419 (99.8%) screened in intervention clinics, versus 8,419 enrolled and 1,108 (13.1%) screened in control clinics. Incidence ratios (IR) of early, advanced and all breast cancers were 2.9 (95% CI 1.1-9.2), 1.0 (0.3-3.5) and 1.9 (0.9-4.1) in the first (screening) year of the trial, and the cumulative IR for all breast cancers converged to 1.4 (0.7-2.8) by the end of follow-up (Year 2). Eighteen (69.2%) of 26 women with early stage disease had breast conservation surgery (BCS) versus 6 (42.5%) of 14 women with late-stage disease (p = 0.02). Fifteen (68.2%) of 22 women with breast cancer in the intervention group had BCS versus nine (50.0%) of 18 women in the control group (p = 0.34). Well-designed opportunistic clinic-based breast cancer screening programs may be useful for early breast cancer detection in LMICs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.