ReviewNeuropsychology review2015
Proton Magnetic Resonance Spectroscopy: Relevance of Glutamate and GABA to Neuropsychology.
Review in Neuropsychology review, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed.
- Ultra-high field magnetic resonance spectroscopy study of transcranial magnetic stimulation treatment in adolescents with depression.BMC psychiatry · 2026Trial
- A multimethod examination of impulsivity and its association with gamma-aminobutyric acid (GABA), glutamate, and other neurometabolite levels in youth who do and do not use alcohol.Addictive behaviors · 2025Article
- Prefrontal inhibitory mechanisms associated with Putamen activity during valence learning revealed by multimodal fMRI-fMRS.Communications biology · 2025Article
- Functional connectivity and GABAergic signaling modulate the enhancement effect of neurostimulation on mathematical learning.PLoS biology · 2025Article
- GABA Levels Are Significantly Reduced in the Visual, Motor, and Auditory Cortex of Patients with Mild Cognitive Impairment.Aging and disease · 2025Article
- Potential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review.Addiction neuroscience · 2025Article
- Review
- Chronic unpredictable mild stress induces anxiety-like behavior in female C57BL/6N mice, accompanied by alterations in inflammation and the kynurenine pathway of tryptophan metabolism.Frontiers in neuroscience · 2025Article
- GABAergic inhibition in human hMT+ predicts visuo-spatial intelligence mediated through the frontal cortex.eLife · 2024Article
- GABA levels decline with age: A longitudinal study.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Cortical GABA Levels Are Reduced in Post-Acute COVID-19 Syndrome.Brain sciences · 2023Article
- Effects of acute physical activity on brain metabolites as measured by magnetic resonance spectroscopy (Heliyon · 2023Article
- Severity of prematurity and age impact early postnatal development of GABA and glutamate systems.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- A neurophysiological signature of dynamic emotion recognition associated with social communication skills and cortical gamma-aminobutyric acid levels in children.Frontiers in neuroscience · 2023Article
- Undercarboxylated, But Not Carboxylated, Osteocalcin Suppresses TNF-α-Induced Inflammatory Signaling Pathway in Myoblasts.Journal of the Endocrine Society · 2022Article
- Quantifying GABA in Addiction: A Review of Proton Magnetic Resonance Spectroscopy Studies.Brain sciences · 2022Review
- Electrophysiological resting-state hyperconnectivity and poorer behavioural regulation as predisposing profiles of adolescent binge drinking.Addiction biology · 2022Article
- Examination of gamma-aminobutyric acid and glutamate-glutamine levels in association with impulsive behavior in adolescent marijuana users.Drug and alcohol dependence · 2022Article
- Dignity neuroscience: universal rights are rooted in human brain science.Annals of the New York Academy of Sciences · 2021Review
- GABA and glutamate in the preterm neonatal brain: In-vivo measurement by magnetic resonance spectroscopy.NeuroImage · 2021Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proton Magnetic Resonance Spectroscopy (MRS) has been widely used to study the healthy and diseased brain in vivo. The availability of whole body MR scanners with a field strength of 3 Tesla and above permit the quantification of many metabolites including the neurotransmitters glutamate (Glu) and γ-aminobutyric acid (GABA). The potential link between neurometabolites identified by MRS and cognition and behavior has been explored in numerous studies both in healthy subjects and in patient populations. Preliminary findings suggest direct or opposite associations between GABA or Glu with impulsivity, anxiety, and dexterity. This chapter is intended to provide an overview of basic principles of MRS and the literature reporting correlations between GABA or Glu and results of neuropsychological assessments.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.