Evidence map›Paper›PMID 26264271›Full record

ArticleBMC research notes2015

Afrostyrax lepidophyllus extracts exhibit in vitro free radical scavenging, antioxidant potential and protective properties against liver enzymes ion mediated oxidative damage.

Bruno Moukette Moukette, Constant Anatole Pieme, Prosper Cabral Nya Biapa, Vicky Jocelyne Ama Moor, Eustace Berinyuy, Jeanne Yonkeu Ngogang

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Domestication of a WildJournal of fungi (Basel, Switzerland) · 2026
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  3. Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  4. Evidence-based complementary and alternative medicine : eCAM · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bruno Moukette MouketteLaboratory of Biochemistry, Department of Physiological Sciences and Biochemistry, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, PO Box 1364, Yaoundé, Cameroon. mouket2006@yahoo.fr.
Constant Anatole PiemeLaboratory of Biochemistry, Department of Physiological Sciences and Biochemistry, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, PO Box 1364, Yaoundé, Cameroon. apieme@yahoo.fr.
Prosper Cabral Nya BiapaDepartment of Biochemistry, Faculty of Science, University of Dschang, PO Box 67, Dschang, Cameroon. brbiapa@yahoo.fr.
Vicky Jocelyne Ama MoorLaboratory of Biochemistry, Department of Physiological Sciences and Biochemistry, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, PO Box 1364, Yaoundé, Cameroon. movicky@yahoo.fr.
Eustace BerinyuyLaboratory of Biochemistry, Department of Physiological Sciences and Biochemistry, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, PO Box 1364, Yaoundé, Cameroon. eusbong@yahoo.com.
Jeanne Yonkeu NgogangLaboratory of Biochemistry, Department of Physiological Sciences and Biochemistry, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, PO Box 1364, Yaoundé, Cameroon. jngogang@yahoo.fr.
Université de Yaoundé I · CMUniversité de Dschang · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies described the phytochemical constituents of plants in relation with the free radical scavenging property and inhibition of lipid peroxidation. This study investigated the in vitro antioxidant property, and the protective effects of ethanolic and aqueous ethanol extract of the leaves and barks of Afrostyrax lepidophyllus (Huaceae) against ion mediated oxidative damages.

methodsFour extracts (ethanol and aqueous-ethanol) from the leaves and barks of A. lepidophyllus were used in this study. The total phenols content, the antiradical and antioxidant properties were determined using standard colorimetric methods.

resultsThe plant extracts had a significant scavenging potential on the 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl (OH), nitrite oxide (NO) and 2,2-azinobis (3-ethylbenzthiazoline)-6-sulfonic acid (ABTS) radicals with the IC50 varied between 47 and 200 µg/mL depending on the part of plant and the type of extract. The ethanol extract of A. lepidophyllus bark (GEE) showed the highest polyphenolic (35.33 ± 0.29) and flavonoid (12.00 ± 0.14) content. All the tested extracts demonstrated a high protective potential with the increased of superoxide dismutase, catalase and peroxidase activities.

conclusionAfrostyrax lepidophyllus extracts exhibited higher antioxidant potential and significant protective potential on liver enzymes.

Indexed as

Free Radical ScavengersTreesAnimalsAntioxidantsBenzothiazolesBiphenyl CompoundsCatalaseColorimetryEthanolFlavonoidsFree RadicalsHydroxyl RadicalInhibitory Concentration 50IonsLipid PeroxidationLiver1,1-diphenyl-2-picrylhydrazyl2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidAntioxidantsBenzothiazolesBiphenyl CompoundsCatalaseEthanolFlavonoidsFree RadicalsFree Radical ScavengersHydroxyl RadicalIonsMolybdenumNitric OxideOxygenPeroxidasePhenolPicratesPlant ExtractsSulfonic AcidsSuperoxide Dismutase

Identifiers

PMID26264271
PMCPMC4534151
OpenAlexW1874079362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.