Evidence map›Paper›PMID 26264168›Full record

ArticleTechniques in coloproctology2015

Managing perianal Crohn's fistula in the anti-TNFα era.

P Tozer, D W Borowski, A Gupta, N Yassin, R Phillips, A Hart

Abstract read
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In one paragraph

Article in Techniques in coloproctology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

P TozerFistula Research Unit, St Mark's Hospital, Imperial College London, London, UK. philtozer@doctors.org.uk.
D W BorowskiUniversity Hospital North Tees, Stockton on Tees, Cleveland, UK.
A GuptaFistula Research Unit, St Mark's Hospital, Imperial College London, London, UK.
N YassinFistula Research Unit, St Mark's Hospital, Imperial College London, London, UK.
R PhillipsFistula Research Unit, St Mark's Hospital, Imperial College London, London, UK.
A HartFistula Research Unit, St Mark's Hospital, Imperial College London, London, UK.
Imperial College London · GBSt Mark's Hospital · GBUniversity Hospital of North Tees · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perianal fistulas in Crohn's disease are common and difficult to treat. Their aetiology is poorly understood. Assessment is clinical, endoscopic and radiological, and management is undertaken by a multidisciplinary team of gastroenterologists, surgeons and radiologists. Surgical drainage of the fistula tract system with the placement of loose setons precedes combined therapy with immunosuppressant and anti-TNFα agents in most patients. Proctitis should be rigorously eliminated where possible. Definitive surgical repair is sometimes possible and diversion or proctectomy are occasionally required. Combined medical and surgical management represents a promising avenue for the future.

Indexed as

AdalimumabAnti-Inflammatory AgentsCertolizumab PegolCombined Modality TherapyCrohn DiseaseGastrointestinal AgentsHumansImmunosuppressive AgentsInfliximabPatient Care TeamRectal FistulaRemission InductionTumor Necrosis Factor-alphaAdalimumabAnti-Inflammatory AgentsCertolizumab PegolGastrointestinal AgentsImmunosuppressive AgentsInfliximabTumor Necrosis Factor-alphaAnti-tumour necrosis factor-αBiological therapiesCrohn’s diseasePerianal fistulaSurgery

Identifiers

PMID26264168
OpenAlexW1201953305

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.