SynthesisBMC public health2015
Alcohol intake and associated risk of major cardiovascular outcomes in women compared with men: a systematic review and meta-analysis of prospective observational studies.
Synthesis in BMC public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Reporting bias in the literature on the associations of health-related behaviors and statins with cardiovascular disease and all-cause mortality.PLoS biology · 2018Pooled it
- Association of obstructive sleep apnoea with the risk of vascular outcomes and all-cause mortality: a meta-analysis.BMJ open · 2017Pooled it
- Factors that facilitate treatment uptake for women with alcohol use disorders in high-income countries: A systematic review.Women's health (London, England)Pooled it
- Benefits and Risks of Moderate Alcohol Consumption on Cardiovascular Disease: Current Findings and Controversies.Nutrients · 2019Trial
- Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records.BMJ (Clinical research ed.) · 2017Trial
- Cardiac Responses to Alcohol: A Review of Mechanisms and Clinical Implications.Reviews in cardiovascular medicine · 2026Review
- Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025.Arquivos brasileiros de cardiologia · 2025Article
- Artificial Sweeteners and Cardiovascular Risk in Hungary: Beyond Traditional Risk Factors.Journal of clinical medicine · 2025Article
- Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Article
- Prevention and control of cardiovascular disease in "real-world" settings: sustainable implementation of effective policies.Frontiers in cardiovascular medicine · 2024Review
- Development and validation of risk prediction model for refeeding syndrome in neurocritical patients.Frontiers in nutrition · 2023Article
- Prevalence of prehypertension and hypertension among the adults in South Asia: A multinomial logit model.Frontiers in public health · 2022Article
- Crosstalk between high-density lipoproteins and endothelial cells in health and disease: Insights into sex-dependent modulation.Frontiers in cardiovascular medicine · 2022Review
- Alcohol, cardiovascular disease and industry funding: A co-authorship network analysis of systematic reviews.Social science & medicine (1982) · 2021Article
- Sex differences in the association between green tea consumption and hypertension in elderly Chinese adults.BMC geriatrics · 2021Article
- Describing a new food group classification system for UK biobank: analysis of food groups and sources of macro- and micronutrients in 208,200 participants.European journal of nutrition · 2021Article
- Synergistic Effects of Aldehyde Dehydrogenase 2 Polymorphisms and Alcohol Consumption on Cognitive Impairment after Ischemic Stroke in Han Chinese.Behavioural neurology · 2021Article
- Administration of a putative pro-dopamine regulator, a neuronutrient, mitigates alcohol intake in alcohol-preferring rats.Behavioural brain research · 2020Article
- Effects of Alcohol on the Cardiovascular System in Women.Alcohol research : current reviews · 2020Review
- Consumption of Alcoholic Beverages and the Prevalence of Metabolic Syndrome and Its Components.Nutrients · 2019Article
Corrections and comments
- Commented on by
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of alcohol intake is increasing among women in some populations. Alcohol consumption plays an important role in the risk of major cardiovascular outcomes and total mortality. Here, we conducted a meta-analysis to estimate the association between alcohol intake and major cardiovascular outcomes or total mortality in women compared with men.
methodsWe searched the PubMed, Embase, and the Cochrane Library databases for relevant articles published prior to June 2014. Among these potential included prospective studies, the different dose categories of alcohol intake were compared with the lowest alcohol intake or non-drinkers between women and men for the outcomes of major cardiovascular or total mortality.
resultsWe included 23 prospective studies (18 cohorts) reporting data on 489,696 individuals. The summary relative risk ratio (RRR; female to male) for total mortality was significantly increased with moderate alcohol intake compared with the lowest alcohol intake (RRR, 1.10; 95 % confidence interval [CI]: 1.00-1.21; P = 0.047); no such significance was observed with other levels of alcohol intake (low intake: RRR, 1.07; 95 % CI: 0.98-1.17; P = 0.143; heavy intake: RRR, 1.09; 95 % CI: 0.99-1.21; P = 0.084). There was no evidence of a sex difference in the relative risk for coronary disease, cardiac death, stroke, or ischemic stroke between participants with low to heavy alcohol intake compared with those who never consumed alcohol or had the lowest alcohol intake.
conclusionsWomen with moderate to heavy alcohol intake had a significantly increased risk of total mortality compared with men in multiple subpopulations. Control of alcohol intake should be considered for women, particularly for young women who may be susceptible to binge drinking.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.