Evidence map›Paper›PMID 26263956›Full record

ArticleAnnals of the Royal College of Surgeons of England2015

Radiological considerations and surgical planning in the treatment of giant parathyroid adenomas.

G Garas, M Poulasouchidou, A Dimoulas, P Hytiroglou, M Kita, E Zacharakis

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Annals of the Royal College of Surgeons of England, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Robotics in otorhinolaryngology - head and neck surgery.Annals of the Royal College of Surgeons of England · 2018
    Review
  9. Article
  10. Article
  11. Article
  12. A rare case of giant parathyroid adenoma presenting with recurrent episodes of pancreatitis.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

G GarasSt. Mary's Hospital, Imperial College London , UK.
M PoulasouchidouHippokration Hospital, Thessaloniki , Greece.
A DimoulasSt Luke's Hospital, Thessaloniki , Greece.
P HytiroglouAristotle University of Thessaloniki , Greece.
M KitaHippokration Hospital, Thessaloniki , Greece.
E ZacharakisSt Luke's Hospital, Thessaloniki , Greece.
Hippocration General Hospital · GRSt. Luke's Hospital · GRAristotle University of Thessaloniki · GRImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant parathyroid adenomas constitute a rare clinical entity, particularly in the developed world. We report the case of a 53-year-old woman where the initial ultrasonography significantly underestimated the size of the lesion. The subsequent size and weight of the adenoma (7 cm diameter, 27 g) combined with the severity of the hypercalcaemia raised the suspicion for the presence of a parathyroid carcinoma. This was later disproven by the surgical and histological findings. Giant parathyroid adenomas are encountered infrequently among patients with primary hyperparathyroidism, and appear to have distinct clinical and biochemical features related to specific genomic alterations. Cross-sectional imaging is mandated in the investigation of parathyroid adenomas presenting with severe hypercalcaemia as ultrasonography alone can underestimate their size and extent. This is important since it can impact on preoperative preparation and planning as well as the consent process as a thoracic approach may prove necessary for certain cases.

Indexed as

AdenomaParathyroid GlandsParathyroid NeoplasmsFemaleHumansHypercalcemiaHyperparathyroidism, PrimaryMiddle AgedRadiographyConsentGiantImagingParathyroid adenomaPrimary hyperparathyroidismSurgery

Identifiers

PMID26263956
PMCPMC4473887
OpenAlexW1971040397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.