Trial reportAnnals of the Royal College of Surgeons of England2015
Durability of giant hiatus hernia repair in 455 patients over 20 years.
Trial report in Annals of the Royal College of Surgeons of England, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 64 citations in OpenAlex.
- Delayed Gastric Emptying Following Laparoscopic Repair of Very Large Hiatus Hernias Impairs Quality of Life.World journal of surgery · 2018Trial
- Intraoperative FLIP to guide revisional hiatal hernia repair: early experience and outcomes.Surgical endoscopy · 2026Article
- Postoperative quality of life after minimally invasive repair of giant hiatal hernias.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Long-term surgical outcomes for the surgical management of complete intrathoracic stomach (CIS).Surgical endoscopy · 2026Article
- Effectiveness of Adjunctive Measures to Limit Recurrence and Reoperation After Laparoscopic Repair of Large Paraesophageal Hernias: A Single-Institution Series.Journal of clinical medicine · 2026Article
- Long-Term Outcomes of Preoperative Botulinum Toxin Use in Abdominal Wall Reconstruction: A Propensity-Matched Analysis of More Than 5000 Patients Over 5 Years.Aesthetic surgery journal. Open forum · 2026Article
- Outcomes of Laparoscopic Hiatal Hernia Repair: A Three-Year Follow-Up Study From a UK Tertiary Centre.Cureus · 2025Article
- Unilateral Lung Agenesis: A Systematic Review of Prevalence, Anatomical Variants, and Clinical Implications.Diagnostics (Basel, Switzerland) · 2025Review
- Long-term durability and temporal pattern of revisional surgery of laparoscopic large hiatal hernia repair.Updates in surgery · 2025Article
- Impact of laparoscopic repair on type III/IV giant paraesophageal hernias: a single-center experience.Hernia : the journal of hernias and abdominal wall surgery · 2023Article
- Dyspnoea improves following composite repair of giant paraoesophageal hernia.Annals of the Royal College of Surgeons of England · 2023Article
- Comment on "Sutured Versus Mesh-augmented Hiatus Hernia Repair: A Systematic Review and Meta-analysis of Randomized Controlled Trials".Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022Article
- Article
- The use of biosynthetic mesh in giant hiatal hernia repair: is there a rationale? A 3-year single-center experience-author's reply.Hernia : the journal of hernias and abdominal wall surgery · 2021Article
- Preoperative botulinum toxin type A: A case report of a proposed new strategy for giant hiatal hernia management.Clinical case reports · 2020Article
- Comment to: the use of biosynthetic mesh in giant hiatal hernia repair: is there a rationale? A 3-year single-center experience.Hernia : the journal of hernias and abdominal wall surgery · 2020Article
- Giant paraesophageal hernia: What do we really know?JTCVS techniques · 2020Article
- Long-term outcomes following surgical repair of giant paraoesophageal hiatus hernia.Surgical endoscopy · 2019Article
- Treatment of giant paraesophageal hernia: pro laparoscopic approach.Hernia : the journal of hernias and abdominal wall surgery · 2018Review
- Surgical Treatment of Paraesophageal Hernias: A Review.Journal of laparoendoscopic & advanced surgical techniques. Part A · 2016Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe surgical management of symptomatic giant hiatus hernia (GHH) aims to improve quality of life (QoL) and reduce the risk of life threatening complications. Previous reports are predominantly those with small sample sizes and short follow-up periods. The present study sought to assess a large cohort of patients for recurrence and QoL over a longer time period.
methodsThis was a follow-up study of a prospectively collected database of 455 consecutive patients. Primary repair of GHH was evaluated by endoscopy/barium meal for recurrence and a standardised symptom questionnaire for QoL. Recurrence was assessed for size, elapsed time, oesophagitis and symptoms.
resultsObjective and subjective review was achieved in 91.9% and 68.6% of patients. The median age was 69 years (range: 15-93 years) and 64% were female. Laparoscopic repair was completed in 95% (mesh in 6% and Collis gastroplasty in 7%). The 30-day mortality rate was 0.9%. The proportion of patients alive at five and ten years were 90% and 75% respectively. Postoperative QoL scores improved from a mean of 95 to 111 (p<0.01) and were stable over time (112 at 10 years). The overall recurrence rate was 35.6% (149/418) at 42 months; this was 11.5% (48/418) for hernias >2cm and 24.2% (101/418) for <2cm. The rate of new recurrence at 0-1 years was 13.7% (>2cm = 3.4%, <2cm = 10.3%), at 1-5 years it was 30.8% (>2cm = 9.5%, <2cm = 21.3%), at 5-10 years it was 40.1% (>2cm = 13.8%, <2cm = 26.3%) and at over 10 years it was 50.0% (>2cm = 25.0%, <2cm = 25.0%). Recurrence was associated with oesophagitis but not decreased QoL. Revision surgery was required in 4.8% of cases (14.8% with recurrence). There were no interval major GHH complications.
conclusionsSurgery has provided sustained QoL improvements irrespective of recurrence. Recurrence occurred progressively over ten years and may predispose to oesophagitis.
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