Evidence map›Paper›PMID 26263417›Full record

ArticleJournal of biomedical optics2015

Performance characteristics of an interventional multispectral photoacoustic imaging system for guiding minimally invasive procedures.

Wenfeng Xia, Daniil I Nikitichev, Jean Martial Mari, Simeon J West, Rosalind Pratt, Anna L David, Sebastien Ourselin, Paul C Beard, Adrien E Desjardins

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of biomedical optics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Functional Photoacoustic Imaging for Placental Monitoring: A Mini Review.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Photoacoustic image-guided interventions.Experimental biology and medicine (Maywood, N.J.) · 2020
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Wenfeng Xia *University College London, Department of Medical Physics and Biomedical Engineering, Gower Street, London WC1E 6BT, United Kingdom.
Daniil I Nikitichev *University College London, Department of Medical Physics and Biomedical Engineering, Gower Street, London WC1E 6BT, United Kingdom.
Jean Martial MariUniversity College London, Department of Medical Physics and Biomedical Engineering, Gower Street, London WC1E 6BT, United Kingdom.
Simeon J WestUniversity College Hospital, Department of Anaesthesia, Main Theatres, Maple Bridge Link Corridor, Podium 3, 235 Euston Road, London NW1 2BU, United Kingdom.
Rosalind PrattUniversity College London, Institute for Women's Health, 86-96 Chenies Mews, London WC1E 6HX, United Kingdom.
Anna L DavidUniversity College London, Institute for Women's Health, 86-96 Chenies Mews, London WC1E 6HX, United Kingdom.
Sebastien OurselinUniversity College London, Center for Medical Imaging Computing, Gower Street, London WC1E 6BT, United Kingdom.
Paul C BeardUniversity College London, Department of Medical Physics and Biomedical Engineering, Gower Street, London WC1E 6BT, United Kingdom.
Adrien E DesjardinsUniversity College London, Department of Medical Physics and Biomedical Engineering, Gower Street, London WC1E 6BT, United Kingdom.
University College London · GBUniversity College Hospital · GB

Funding

European Research Council 310970Wellcome Trust 101957
6 · The paper itself

Abstract

Precise device guidance is important for interventional procedures in many different clinical fields including fetal medicine, regional anesthesia, interventional pain management, and interventional oncology. While ultrasound is widely used in clinical practice for real-time guidance, the image contrast that it provides can be insufficient for visualizing tissue structures such as blood vessels, nerves, and tumors. This study was centered on the development of a photoacoustic imaging system for interventional procedures that delivered excitation light in the ranges of 750 to 900 nm and 1150 to 1300 nm, with an optical fiber positioned in a needle cannula. Coregistered B-mode ultrasound images were obtained. The system, which was based on a commercial ultrasound imaging scanner, has an axial resolution in the vicinity of 100  μm and a submillimeter, depth-dependent lateral resolution. Using a tissue phantom and 800 nm excitation light, a simulated blood vessel could be visualized at a maximum distance of 15 mm from the needle tip. Spectroscopic contrast for hemoglobin and lipids was observed with ex vivo tissue samples, with photoacoustic signal maxima consistent with the respective optical absorption spectra. The potential for further optimization of the system is discussed.

Indexed as

Elasticity Imaging TechniquesEquipment DesignEquipment Failure AnalysisMinimally Invasive Surgical ProceduresMolecular ImagingPhantoms, ImagingPhotoacoustic TechniquesReproducibility of ResultsSensitivity and SpecificitySpectrum AnalysisSurgery, Computer-Assisted

Identifiers

PMID26263417
PMCPMC5217184
OpenAlexW1492966311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.