ReviewMarine drugs2015
Porifera Lectins: Diversity, Physiological Roles and Biotechnological Potential.
Review in Marine drugs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 43 citations in OpenAlex.
- Phagocytosis of microbial symbionts supports embryonic nutrition in the sponge Halichondria panicea.Microbiome · 2026Article
- Structural Characterization of a Proto-Type Galectin fromMicroorganisms · 2026Article
- Ammonia oxidation and recalcitrant carbon degradation fuel mixotrophic growth in the symbiont community of a deep-sea sponge.Microbiome · 2026Article
- Sponge Galectins: Structure, Evolution, and Function.ACS omega · 2026Review
- Afil, a Lectin fromMicroorganisms · 2025Article
- Novel Galectins Purified from the SpongeMarine drugs · 2024Article
- A Genomic and Transcriptomic Analysis of the C-Type Lectin Gene Family Reveals Highly Expanded and Diversified Repertoires in Bivalves.Marine drugs · 2023Article
- A brief history of galectin evolution.Frontiers in immunology · 2023Article
- On the origin of the functional versatility of macrophages.Frontiers in physiology · 2023Article
- The role of Jacalin-related lectin gene AOL_s00083g511 in the development and pathogenicity of the nematophagous fungus Arthrobotrys oligospora.Journal of microbiology (Seoul, Korea) · 2021Article
- Glycan-to-Glycan Binding: Molecular Recognition through Polyvalent Interactions Mediates Specific Cell Adhesion.Molecules (Basel, Switzerland) · 2021Review
- The Challenge of the SpongeGenes · 2019Article
- Soritesidine, a Novel Proteinous Toxin from the Okinawan Marine SpongeMarine drugs · 2019Article
- Differential expression of immune receptors in two marine sponges upon exposure to microbial-associated molecular patterns.Scientific reports · 2018Article
- Biochemical characterisation of lectin from Indian hyacinth plant bulbs with potential inhibitory action against human cancer cells.International journal of biological macromolecules · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An overview on the diversity of 39 lectins from the phylum Porifera is presented, including 38 lectins, which were identified from the class of demosponges, and one lectin from the class of hexactinellida. Their purification from crude extracts was mainly performed by using affinity chromatography and gel filtration techniques. Other protocols were also developed in order to collect and study sponge lectins, including screening of sponge genomes and expression in heterologous bacterial systems. The characterization of the lectins was performed by Edman degradation or mass spectrometry. Regarding their physiological roles, sponge lectins showed to be involved in morphogenesis and cell interaction, biomineralization and spiculogenesis, as well as host defense mechanisms and potentially in the association between the sponge and its microorganisms. In addition, these lectins exhibited a broad range of bioactivities, including modulation of inflammatory response, antimicrobial and cytotoxic activities, as well as anticancer and neuromodulatory activity. In view of their potential pharmacological applications, sponge lectins constitute promising molecules of biotechnological interest.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.