Evidence map›Paper›PMID 26262579›Full record

ReviewCurrent opinion in pediatrics2015

Computational modeling and engineering in pediatric and congenital heart disease.

Alison L Marsden, Jeffrey A Feinstein

Abstract readReview
In one paragraph

Review in Current opinion in pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Postnatal pulmonary artery development from transcript to tissue.Journal of the Royal Society, Interface · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Computational fluid dynamics of bladder voiding using 3D dynamic MRI.International journal for numerical methods in biomedical engineering · 2024
    Article
  8. Article
  9. Article
  10. Effects of cardiac growth on electrical dyssynchrony in the single ventricle patient.Computer methods in biomechanics and biomedical engineering · 2024
    Article
  11. Branched Latent Neural Maps.Computer methods in applied mechanics and engineering · 2024
    Article
  12. Article
  13. Article
  14. An Automated View Classification Model for Pediatric Echocardiography Using Artificial Intelligence.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alison L MarsdenaDepartments of Pediatrics and Bioengineering, Institute for Computational and Mathematical Engineering bDepartments of Pediatrics and Bioengineering, Stanford University, Stanford, California, USA.
Jeffrey A Feinstein

Funding

Shear Stress and Light-Sheets to Study Cardiac TrabeculationR01HL129727 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSIAI, TZUNG K, MARSDEN, ALISON L · 2015 to 2024
$3.5M
Patient-specific simulations for thrombotic risk assessment in Kawasaki diseaseR21HL102596 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MARSDEN, ALISON L · 2010 to 2011
$405k
NHLBI NIH HHS R01 HL129727NHLBI NIH HHS R21 HL102596
6 · The paper itself

Abstract

purpose of reviewRecent methodological advances in computational simulations are enabling increasingly realistic simulations of hemodynamics and physiology, driving increased clinical utility. We review recent developments in the use of computational simulations in pediatric and congenital heart disease, describe the clinical impact in modeling in single-ventricle patients, and provide an overview of emerging areas. RECENT

findingsMultiscale modeling combining patient-specific hemodynamics with reduced order (i.e., mathematically and computationally simplified) circulatory models has become the de-facto standard for modeling local hemodynamics and 'global' circulatory physiology. We review recent advances that have enabled faster solutions, discuss new methods (e.g., fluid structure interaction and uncertainty quantification), which lend realism both computationally and clinically to results, highlight novel computationally derived surgical methods for single-ventricle patients, and discuss areas in which modeling has begun to exert its influence including Kawasaki disease, fetal circulation, tetralogy of Fallot (and pulmonary tree), and circulatory support. SUMMARY: Computational modeling is emerging as a crucial tool for clinical decision-making and evaluation of novel surgical methods and interventions in pediatric cardiology and beyond. Continued development of modeling methods, with an eye towards clinical needs, will enable clinical adoption in a wide range of pediatric and congenital heart diseases.

Indexed as

ChildChild, PreschoolComputer SimulationHeart Defects, CongenitalHeart VentriclesHemodynamicsHumansPediatricsPrecision Medicine

Identifiers

PMID26262579
PMCPMC4666705

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.