ArticleTranslational psychiatry2015
Atypical spatiotemporal signatures of working memory brain processes in autism.
Article in Translational psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Neural dysfunctions associated with atypical memory in ASD: an ALE meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Brain correlates of declarative memory atypicalities in autism: a systematic review of functional neuroimaging findings.Molecular autism · 2023Pooled it
- β-hydroxybutyrate restores social deficits by suppressing HDAC9 in the ACC of Shank3B-deficient mice.EMBO molecular medicine · 2026Article
- Theta-gamma phase amplitude coupling serves as a marker of social cognition and visual working memory deficits in individuals with elevated autistic traits.Communications psychology · 2026Article
- Association between theta-band resting-state functional connectivity and declarative memory abilities in children.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Multi-kernel Learning Fusion Algorithm Based on RNN and GRU for ASD Diagnosis and Pathogenic Brain Region Extraction.Interdisciplinary sciences, computational life sciences · 2024Article
- GAT-LI: a graph attention network based learning and interpreting method for functional brain network classification.BMC bioinformatics · 2021Article
- Preeclampsia and Neurodevelopmental Outcomes: Potential Pathogenic Roles for Inflammation and Oxidative Stress?Molecular neurobiology · 2021Review
- Article
- Neural correlates of cognitive variability in childhood autism and relation to heterogeneity in decision-making dynamics.Developmental cognitive neuroscience · 2020Article
- Article
- Neural correlates of verbal working memory in children with epilepsy with centro-temporal spikes.NeuroImage. Clinical · 2020Article
- Frequency-specific neural synchrony in autism during memory encoding, maintenance and recognition.Brain communications · 2020Article
- Frontoparietal Network Connectivity During anFrontiers in psychiatry · 2020Article
- Diagnosis of Autism Spectrum Disorder Using Central-Moment Features From Low- and High-Order Dynamic Resting-State Functional Connectivity Networks.Frontiers in neuroscience · 2020Article
- Prefrontal high gamma during a magnetoencephalographic working memory task.Human brain mapping · 2019Article
- Enhancing the representation of functional connectivity networks by fusing multi-view information for autism spectrum disorder diagnosis.Human brain mapping · 2019Article
- Load matters: neural correlates of verbal working memory in children with autism spectrum disorder.Journal of neurodevelopmental disorders · 2018Article
- Theta and Alpha Oscillation Impairments in Autistic Spectrum Disorder Reflect Working Memory Deficit.Scientific reports · 2017Article
- Dynamic functional connectivity shapes individual differences in associative learning.Human brain mapping · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Working memory (WM) impairments may contribute to the profound behavioural manifestations in children with autism spectrum disorder (ASD). However, previous behavioural results are discrepant as are the few functional magnetic resonance imaging (fMRI) results collected in adults and adolescents with ASD. Here we investigate the precise temporal dynamics of WM-related brain activity using magnetoencephalography (MEG) in 20 children with ASD and matched controls during an n-back WM task across different load levels (1-back vs 2-back). Although behavioural results were similar between ASD and typically developing (TD) children, the between-group comparison performed on functional brain activity showed atypical WM-related brain processes in children with ASD compared with TD children. These atypical responses were observed in the ASD group from 200 to 600 ms post stimulus in both the low- (1-back) and high- (2-back) memory load conditions. During the 1-back condition, children with ASD showed reduced WM-related activations in the right hippocampus and the cingulate gyrus compared with TD children who showed more activation in the left dorso-lateral prefrontal cortex and the insulae. In the 2-back condition, children with ASD showed less activity in the left insula and midcingulate gyrus and more activity in the left precuneus than TD children. In addition, reduced activity in the anterior cingulate cortex was correlated with symptom severity in children with ASD. Thus, this MEG study identified the precise timing and sources of atypical WM-related activity in frontal, temporal and parietal regions in children with ASD. The potential impacts of such atypicalities on social deficits of autism are discussed.
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Registered trials
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