ArticleInternational journal of clinical and experimental pathology2015
Distant dissemination of mixed low-grade astroblastoma-arteriovenous malformation after initial operation: a case report.
Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- A case of disseminated spinal astroblastoma harboring a MAMLD1::BEND2 fusion.Neuropathology : official journal of the Japanese Society of Neuropathology · 2024Article
- Spinal astroblastoma: a rare tumour in an unusual location.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Identification of two core genes in glioblastomas with different isocitrate dehydrogenase mutation status.Molecular biology reports · 2020Article
- Astroblastoma - a rare and challenging tumor: a case report and review of the literature.Journal of medical case reports · 2018Review
- Patterns of care and survival outcomes in patients with astroblastoma: an individual patient data analysis of 152 cases.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- IDH-1R132H mutation status in diffuse glioma patients: implications for classification.Oncotarget · 2016Article
- A case of astroblastoma: Radiological and histopathological characteristics and a review of current treatment options.Surgical neurology international · 2016Article
- High-Grade Intraventricular Astroblastoma in a Young Adult: A Rare and Controversial Tumor to Manage.Asian journal of neurosurgeryArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a rare case of low-grade astroblastoma coexisting with an arteriovenous malformation (AVM) underwent surgery two times in a 38-year-old man. After the first surgery, this case was reported as a mixed low-grade astroblastoma and AVM. The lesion was completely resected surgically along with AVM. The patient underwent postoperative radiotherapy. Twenty months later, MRI showed enhanced lesions in suprasellar, pineal region and multiple small lesions in the spinal cord, whereas completely no recurrent lesion at the primary tumor site. So, the patient rationally underwent surgical removal in suprasellar and pineal region. After the second surgery, this case was diagnosed as a high-grade astroblastoma. Cells from the second surgical specimens showed high MIB-1 index and an increased olig-2 index. In addition, it is not common for low-grade astroblastoma metastasis to suprasellar, pineal region and spine with completely no recurrence at the original primary tumor site. Therefore it is difficult to predict tumor behavior and patient's clinical outcome merely based on histologic features. The important issue is whether the AVM was thought to be the cause of poor progress of this tumor. More cases are needed to confirm this. Classification and histogenesis of this tumor is still debated. Lack of clinicopathological correlation makes the prognosis of this tumor unpredictable. Anyway, we should be very discreet to treat the astroblastoma, even for low-grade astroblastoma.
Indexed as
Identifiers
26261652PMC4525986W2185516601What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.