Evidence map›Paper›PMID 26261625›Full record

ArticleInternational journal of clinical and experimental pathology2015

Changes of monocyte subsets in patients with acute coronary syndrome and correlation with myocardial injury markers.

Li Zhu, Yigang Yin, Ruifang Zhou, Jie Lin, Jianming Li, Jun Ye

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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  5. CTRP3 induces an intermediate switch of CD14Experimental and therapeutic medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Li ZhuDepartment of Laboratory Medicine, Taizhou People's Hospital Taizhou 225300, Jiangsu Province, China.
Yigang YinDepartment of Laboratory Medicine, Taizhou People's Hospital Taizhou 225300, Jiangsu Province, China.
Ruifang ZhouTaizhou Polytechnic College Taizhou, China.
Jie LinDepartment of Laboratory Medicine, Taizhou People's Hospital Taizhou 225300, Jiangsu Province, China.
Jianming LiDepartment of Laboratory Medicine, Taizhou People's Hospital Taizhou 225300, Jiangsu Province, China.
Jun YeDepartment of Laboratory Medicine, Taizhou People's Hospital Taizhou 225300, Jiangsu Province, China.
Nantong University · CNTaizhou Vocational and Technical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the changes of peripheral blood monocytes subsets in acute coronary syndrome (ACS) and its clinical significance.

methodsA total of 68 ACS patients and 27 healthy subjects (HS) were enrolled. Monocyte subset analysis was performed using flow cytometry: CD14++CD16-(Mon1), CD14++CD16+ (Mon2), and CD14+CD16++ (Mon3).

results1. The number of Mon1 and Mon3 were significantly increased in ACS patients compared with HS (P<0.05) and Mon2 decreased in ACS patients (P<0.05). 2. The number of Mon1, Mon2, Mon3 was positively correlated with WBC count (P<0.05). The Mon2% was negatively correlated with the serum levels of LDH, CK, CK-MB (P<0.05). The number of Mon1, Mon3 was positively correlated with the serum levels of LDH, CK, CK-MB (P<0.05).

conclusionThe changes in different subsets of monocytes may be associated with pathogenesis of ACS and myocardial injury. The findings might be useful in the assessment of myocardial injury.

Indexed as

Acute Coronary SyndromeAgedBiomarkersCase-Control StudiesCreatine Kinase, MB FormFemaleFlow CytometryGPI-Linked ProteinsHumansLipopolysaccharide ReceptorsL-Lactate DehydrogenaseMaleMiddle AgedMonocytesMyocardiumPredictive Value of TestsBiomarkersCreatine Kinase, MB FormFCGR3B protein, humanGPI-Linked ProteinsLipopolysaccharide ReceptorsL-Lactate DehydrogenaseReceptors, IgGAcute coronary syndromeCD14CD16monocytes

Identifiers

PMID26261625
PMCPMC4525959
OpenAlexW2412138818

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.