ReviewCold Spring Harbor perspectives in biology2015
Biological Scaling Problems and Solutions in Amphibians.
Review in Cold Spring Harbor perspectives in biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Boreal Toad Survival Varies by Degree of Attenuation and Adaptation of a Fungal Pathogen.EcoHealth · 2026Article
- Ploidy and neuron size impact nervous system development and function in Xenopus.Cell reports · 2026Article
- Optimized toolkit for the manipulation of immortalized axolotl fibroblasts.Methods (San Diego, Calif.) · 2025Article
- Genome size evolution and phenotypic correlates in the poison frog family Dendrobatidae.Evolution; international journal of organic evolution · 2025Article
- Epithelial apoptotic pattern emerges from global and local regulation by cell apical area.Current biology : CB · 2023Article
- Article
- Critical review of the phytohemagglutinin assay for assessing amphibian immunity.Conservation physiology · 2023Article
- The Nuclear-to-Cytoplasmic Ratio: Coupling DNA Content to Cell Size, Cell Cycle, and Biosynthetic Capacity.Annual review of genetics · 2022Review
- Ecological and evolutionary trends of body size in Pristimantis frogs, the world's most diverse vertebrate genus.Scientific reports · 2022Article
- Scaling of biosynthesis and metabolism with cell size.Molecular biology of the cell · 2022Article
- Semicircular canal size constrains vestibular function in miniaturized frogs.Science advances · 2022Article
- Signatures of functional bacteriome structure in a tropical direct-developing amphibian species.Animal microbiome · 2022Article
- Specificity of Nuclear Size Scaling in Frog Erythrocytes.Frontiers in cell and developmental biology · 2022Article
- Water constraints drive allometric patterns in the body shape of tree frogs.Scientific reports · 2021Article
- DNA content contributes to nuclear size control inMolecular biology of the cell · 2020Article
- Cell Biology: Social Distancing of Microtubule Ends Increases Their Assembly Rates.Current biology : CB · 2020Article
- Constitutive expression of a fluorescent protein reports the size of live human cells.Molecular biology of the cell · 2019Article
- Spindle assembly in egg extracts of the Marsabit clawed frog, Xenopus borealis.Cytoskeleton (Hoboken, N.J.) · 2018Article
- Manipulation of Ploidy in Caenorhabditis elegans.Journal of visualized experiments : JoVE · 2018Article
- High-quality frozen extracts ofMolecular biology of the cell · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Size is a primary feature of biological systems that varies at many levels, from the organism to its constituent cells and subcellular structures. Amphibians populate some of the extremes in biological size and have provided insight into scaling mechanisms, upper and lower size limits, and their physiological significance. Body size variation is a widespread evolutionary tactic among amphibians, with miniaturization frequently correlating with direct development that occurs without a tadpole stage. The large genomes of salamanders lead to large cell sizes that necessitate developmental modification and morphological simplification. Amphibian extremes at the cellular level have provided insight into mechanisms that accommodate cell-size differences. Finally, how organelles scale to cell size between species and during development has been investigated at the molecular level, because subcellular scaling can be recapitulated using Xenopus in vitro systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.