Evidence map›Paper›PMID 26260893›Full record

ArticleAnimal science journal = Nihon chikusan Gakkaiho2016

Immunogenic properties of Landrace pigs selected for resistance to mycoplasma pneumonia of swine.

Liushiqi Borjigin, Tomoyuki Shimazu, Yuki Katayama, Meihua Li, Takumi Satoh, Kouichi Watanabe, Haruki Kitazawa, Sang-gun Roh, Hisashi Aso, Kazuo Katoh and 5 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal science journal = Nihon chikusan Gakkaiho, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Linking Animal Welfare and Antibiotic Use in Pig Farming-A Review.Animals : an open access journal from MDPI · 2022
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Liushiqi BorjiginGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Tomoyuki ShimazuGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Yuki KatayamaGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Meihua LiGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Takumi SatohGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Kouichi WatanabeGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Haruki KitazawaGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Sang-gun RohGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Hisashi AsoGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Kazuo KatohGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Takafumi UchidaGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Yoshihito SudaDepartment of Food, Agriculture and Environment, Miyagi University, Sendai, Japan.
Akiko SakumaMiyagi Prefecture Animal Industry Experiment Station, Miyagi, Japan.
Mituru NakajoMiyagi Prefecture Animal Industry Experiment Station, Miyagi, Japan.
Keiichi SuzukiGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Tohoku University · JPMiyagi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycoplasma pneumonia of swine (MPS) lung lesions and immunogenic properties were compared between a Landrace line that was genetically selected for reduced incidence of pulmonary MPS lesions, and a non-selected Landrace line. The MPS-selected Landrace line showed significantly lower degrees of pulmonary MPS lesions compared with the non-selected Landrace line. When changes in immunity before and after vaccination were compared, the percentage of B cells in the peripheral blood of the MPS-selected Landrace line was significantly lower than that of the non-selected line. Furthermore, the concentration of growth hormone and the mitogen activity of peripheral blood mononuclear cells in the MPS-selected Landrace line showed significantly (P < 0.05) lower increases after vaccination than the non-selected line. Conversely, the concentration of peripheral blood interferon (IFN)-γ and salivary immunoglobulin A (IgA) after Mycoplasma hyopneumoniae vaccination was significantly higher in the MPS-selected Landrace line than in the non-selected line. Gene expression of toll-like receptor (TLR)2 and TLR4 was significantly higher in the MPS-selected Landrace line in immune tissues, with the exception of the hilar lymph nodes. The present results suggest that peripheral blood IFN-γ, salivary IgA TLR2, and TLR4 are important immunological factors influencing the development of MPS lesions.

Indexed as

Selection, GeneticAnimalsBacterial VaccinesB-LymphocytesFemaleGene ExpressionImmunoglobulin AInterferon-gammaMaleMycoplasma hyopneumoniaePneumonia of Swine, MycoplasmalSalivaSwineToll-Like Receptor 2Toll-Like Receptor 4Bacterial VaccinesImmunoglobulin AInterferon-gammaToll-Like Receptor 2Toll-Like Receptor 4disease resistanceimmunogenic propertiesmycoplasma pneumonia lesionspig

Identifiers

PMID26260893
PMCPMC7159536
OpenAlexW1938764419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.