Evidence map›Paper›PMID 26260876›Full record

ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2016

Surgical treatment of liver metastasis of gastric cancer: a retrospective multicenter cohort study (KSCC1302).

Eiji Oki, Shoji Tokunaga, Yasunori Emi, Tetsuya Kusumoto, Manabu Yamamoto, Kengo Fukuzawa, Ikuo Takahashi, Sumiya Ishigami, Akihito Tsuji, Hidefumi Higashi and 10 more

Open access · bronzeAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 2 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 125 citations in OpenAlex.

  1. Guideline
  2. Pooled it
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  6. Article
  7. Practical management of oligometastatic gastric cancer.ESMO gastrointestinal oncology · 2024
    Review
  8. Role of immunotherapy in gastric cancer with liver metastasis.World journal of clinical oncology · 2024
    Article
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 15 institutions in 1 country.

Eiji OkiDepartment of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Fukuoka, 812-8582, Japan. okieiji@surg2.med.kyushu-u.ac.jp.
Shoji TokunagaMedical Information Center, Kyushu University Hospital, Fukuoka, Japan.
Yasunori EmiDepartment of Surgery, Saiseikai Fukuoka General Hospital, Fukuoka, Japan.
Tetsuya KusumotoDepartment of Gastroenterological Surgery/Clinical Research Institute Cancer Research Division, National Kyushu Medical Center, Fukuoka, Japan.
Manabu YamamotoDepartment of Gastroenterological Surgery, National Kyushu Cancer Center, Fukuoka, Japan.
Kengo FukuzawaDepartment of Surgery, Oita Red Cross Hospital, Oita, Japan.
Ikuo TakahashiDepartment of Surgery, Matsuyama Red Cross Hospital, Matsuyama, Japan.
Sumiya IshigamiDepartment of Digestive Surgery, Breast and Thyroid Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Akihito TsujiDepartment of Medical Oncology, Kobe City Medical Center General Hospital, Kobe, Japan.
Hidefumi HigashiDepartment of Surgery, Steel Memorial Yawata Hospital, Kitakyushu, Japan.
Toshihiko NakamuraDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka, Japan.
Hiroshi SaekiDepartment of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Fukuoka, 812-8582, Japan.
Ken ShirabeDepartment of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Fukuoka, 812-8582, Japan.
Yoshihiro KakejiDivision of Gastrointestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Kenji SakaiDepartment of Medical Oncology, Saiseikai Kumamoto Hospital, Kumamoto, Japan.
Hideo BabaDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Tadashi NishimakiDivision of Digestive and General Surgery, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
Shoji NatsugoeDepartment of Digestive Surgery, Breast and Thyroid Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Yoshihiko MaeharaDepartment of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Fukuoka, 812-8582, Japan.
Kyushu Study Group of Clinical Cancer
Kyushu University · JPKagoshima University · JPKobe City Medical Center General Hospital · JPKobe University · JPKumamoto University · JPKyushu Central Hospital of the Mutual Aid Association of Public School Teachers · JPKyushu University Hospital · JPMatsuyama Red Cross Hospital · JPNational Hospital Organization Kyushu Cancer Center · JPNational Kyushu Medical Center · JPNippon Steel Yawata Memorial Hospital · JPOita Red Cross Hospital · JPSaiseikai Fukuoka General Hospital · JPSaiseikai Kumamoto Hospital · JPUniversity of the Ryukyus · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe necessity of surgical treatment of liver metastases of gastric cancer is still controversial. PATIENTS AND

methodsWe conducted a multicenter retrospective cohort study of liver-limited metastasis of gastric cancer treated surgically between 2000 and 2010. In this study, 103 patients were registered, with nine patients excluded from the analysis as they did not meet the eligibility criteria.

resultsOf the 94 patients, 69 underwent surgical resection, 11 underwent surgical resection combined with radiofrequency ablation or microwave coagulation therapy for small or deep tumors, and 14 underwent radiofrequency ablation or microwave coagulation therapy only. Synchronous and metachronous metastases were found in 37 and 57 patients, respectively. The 3- and 5-year overall survival rates of all the patients were 51.4 and 42.3 %, respectively. The 3- and 5-year relapse-free survival rates were 29.2 and 27.7 %, respectively. No significant difference in prognosis was observed between the patients who underwent surgical resection and those who underwent ablation therapy. The patients with hepatic solitary lesions and low-grade lymph node metastases of primary gastric cancer had significantly better overall survival and relapse-free survival.

conclusionsTo our knowledge, this study is the largest series and first multicenter cohort study of liver-limited metastasis of gastric cancer. The study indicated that patients with a single liver metastasis with a grade lower than N2 lymph node metastasis of the primary lesion are the best candidates for liver resection.

Indexed as

AgedCatheter AblationFemaleFollow-Up StudiesGastrectomyHepatectomyHumansLiver NeoplasmsLymphatic MetastasisMaleNeoplasm InvasivenessNeoplasm StagingPrognosisRetrospective StudiesStomach NeoplasmsSurvival RateGastric cancerHepatectomyLiver metastasisRadiofrequency ablation

Identifiers

PMID26260876
OpenAlexW2188596521

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.