Evidence map›Paper›PMID 26260824›Full record

ArticleThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2015

Feasibility of tuberculosis treatment monitoring by video directly observed therapy: a binational pilot study.

R S Garfein, K Collins, F Muñoz, K Moser, P Cerecer-Callu, F Raab, P Rios, A Flick, M L Zúñiga, J Cuevas-Mota and 5 more

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 78 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04134689 nacompletednot on this mapstarted 2020, after this paper: background citation

DOT Selfie: A Mobile Health Intervention With Transfer of Social Bundle Incentives to Increase Treatment Adherence in Tuberculosis Patients in Uganda: A Randomized Control Trial.

TypeinterventionalSponsorUniversity of GeorgiaRan2020 to 2023Enrolled144ConditionsTuberculosisArmsDOT Selfie Intervention, In-person DOT
NCT05865626 nacompletednot on this mapstarted 2018, after this paper: background citation

A Pilot Study to Evaluate Video Observed Treatment Among Tuberculosis Patients From Lambaréné Using an Instant Messenger Application

TypeinterventionalSponsorCentre de Recherche Médicale de LambarénéRan2018 to 2022Enrolled30ConditionsTuberculosisArmsVOT with and without cash incentive
3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  4. eHealth in TB clinical management.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
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  6. Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2019
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

R S GarfeinDivision of Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, USA.
K CollinsDivision of Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, USA.
F MuñozDivision of Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, USA.
K MoserSan Diego County Health and Human Services Agency, San Diego, California, USA.
P Cerecer-CalluInstituto de Servicios de Salud, Tijuana, Baja California, México.
F RaabDepartment of Preventive Medicine and Public Health, University of California, San Diego, La Jolla, USA.
P RiosQualcomm Institute, University of California, San Diego, La Jolla, USA.
A FlickQualcomm Institute, University of California, San Diego, La Jolla, USA.
M L ZúñigaSchool of Social Work, San Diego State University, San Diego, California, USA.
J Cuevas-MotaDivision of Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, USA.
K LiangSan Diego County Health and Human Services Agency, San Diego, California, USA.
G RangelComision de Salud Fronteriza, Sección México-Secretaria de Salud, Tijuana, Baja California, México.
J L BurgosDivision of Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, USA.
T C RodwellDivision of Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, USA.
K PatrickDepartment of Preventive Medicine and Public Health, University of California, San Diego, La Jolla, USA; Qualcomm Institute, University of California, San Diego, La Jolla, USA.

Funding

Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
Drug tourism to Mexico: Impact of Mexicos new drug law on HIV-HCV-TB in US IDUsR01DA031074 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARFEIN, RICHARD S · 2011 to 2015
$3.2M
The Role of Economic Evaluation in Translating HIV/AIDS Behavioral InterventionsK01MH095680 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BURGOS, JOSE LUIS · 2012 to 2016
$902k
Binational Transmission of Multidrug-Resistant Tuberculosis, California & MexicoK01AI083784 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RODWELL, TIMOTHY CHARLES · 2009 to 2012
$487k
Mobile Phone-Based Video Directly Observed Therapy for TuberculosisR21AI088326 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARFEIN, RICHARD S · 2010 to 2011
$415k
NIAID NIH HHS K01 AI083784NIAID NIH HHS K01-AI083784NIAID NIH HHS R21 AI088326NIAID NIH HHS R21-AI088326NIDA NIH HHS R01 DA031074NIDA NIH HHS R01-DA031074-03S1NIDA NIH HHS T32 DA023356NIMH NIH HHS K01 MH095680NIMH NIH HHS K01-MH095680
6 · The paper itself

Abstract

backgroundAlthough directly observed therapy (DOT) is recommended worldwide for monitoring anti-tuberculosis treatment, transportation and personnel requirements limit its use.

objectiveTo evaluate the feasibility and acceptability of 'video DOT' (VDOT), which allows patients to record and transmit medication ingestion via videos watched remotely by health care providers to document adherence.

methodsWe conducted a single-arm trial among tuberculosis (TB) patients in San Diego, California, USA, (n = 43) and Tijuana, Mexico (n = 9) to represent high- and low-resource settings. Pre-/post-treatment interviews assessed participant characteristics and experiences. Adherence was defined as the proportion of observed doses to expected doses.

resultsThe mean age was 37 years (range 18-86), 50% were male, and 88% were non-Caucasian. The mean duration of VDOT use was 5.5 months (range 1-11). Adherence was similar in San Diego (93%) and Tijuana (96%). Compared to time on in-person DOT, 92% preferred VDOT, 81% thought VDOT was more confidential, 89% never/rarely had problems recording videos, and 100% would recommend VDOT to others. Seven (13%) participants were returned to in-person DOT and six (12%) additional participants had their phones lost, broken or stolen.

conclusionsVDOT was feasible and acceptable, with high adherence in both high- and low-resource settings. Efficacy and cost-effectiveness studies are needed.

Indexed as

Medication AdherenceAdolescentAdultAgedAged, 80 and overAntitubercular AgentsCaliforniaCell PhoneCost-Benefit AnalysisDirectly Observed TherapyFeasibility StudiesFemaleHumansMaleMexicoMiddle AgedAntitubercular Agents

Identifiers

PMID26260824
PMCPMC5673092

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.