Evidence map›Paper›PMID 26260643›Full record

ArticleThe Consultant pharmacist : the journal of the American Society of Consultant Pharmacists2015

Changes in Mood in New Enrollees at a Program of All-Inclusive Care for the Elderly.

Scott Martin Vouri, Stephanie M Crist, Siobhan Sutcliffe, Shane Austin

Registry-linked trialAbstract read
In one paragraph

Article in The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04339634 (Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment of COVID-19 in Frail Elderly Adults With Polypharmacy), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04339634 completednot on this mapstarted 2020, after this paper: background citation

Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment of COVID-19 in Frail Elderly Adults With Polypharmacy

TypeobservationalSponsorTabula Rasa HealthCareRan2020 to 2023Enrolled12,873ConditionsCOVID, Drug Effect, Drug Interaction, Adverse Drug EventArmsSimulation of Repurposed Drugs for COVID-19
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Scott Martin VouriDepartment of Pharmacy Practice, St. Louis College of Pharmacy, St. Louis, Missouri, USA.
Stephanie M Crist
Siobhan Sutcliffe
Shane Austin

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
NCATS NIH HHS KL2 TR000450NCATS NIH HHS UL1 TR000448
6 · The paper itself

Abstract

objectivesTo examine changes in mood after nine months of enrollment in a Program of All-Inclusive Care for the Elderly (PACE).

designCohort study.

settingAlexian Brothers PACE, St. Louis, Missouri.

participantsNewly enrolled patients 55 years of age and older, living in the PACE service area, eligible for nursing facility care and able to live safely in the community, with continuous care, for at least nine months (N = 182).

main outcome measuresGeriatric Depression Scale (GDS)-15 score at the pre-admission evaluation (PAE) and the nine-month evaluation (9ME).

resultsOf the 182 patients evaluated, 27% (n = 49) met the definition of depression as defined by the GDS-15 score of ≥ 6 at the PAE. At the 9ME, only 11% of patients met the depression criteria (P < 0.001). Of the patients who met the criteria for depression at the PAE, 80% of patients (n = 39) no longer met these criteria at the 9ME (P = 0.029). Similar findings were observed by age, gender, and race. Greater improvement was observed among those who were depressed at the PAE; the depressed cohort improved by 5.0 points (P < 0.001) on the GDS-15 scale from the PAE to the 9ME, whereas the nondepressed cohort improved by 0.6 points (P = 0.003).

conclusionThe use of PACE as an alternative intervention may be a good option to improve mood in older adults.

Indexed as

AffectAgedAged, 80 and overCohort StudiesCommunity Health ServicesComprehensive Health CareDepressionFemaleHealth Services for the AgedHumansMaleMiddle AgedMissouriOutcome Assessment, Health CarePsychiatric Status Rating ScalesRetrospective Studies

Identifiers

PMID26260643
PMCPMC4605402

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.