ArticleVirology journal2015
Function and diversity of P0 proteins among cotton leafroll dwarf virus isolates.
Article in Virology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Review
- New persistent plant RNA virus carries mutations to weaken viral suppression of antiviral RNA interference.Molecular plant pathology · 2024Article
- Characterization of the proteins encoded by a recently emerged cotton-infecting Polerovirus.Virus genes · 2024Article
- Aphid gene expression following polerovirus acquisition is host species dependent.Frontiers in plant science · 2024Article
- Cotton leafroll dwarf disease: An enigmatic viral disease in cotton.Molecular plant pathology · 2023Review
- Article
- Prospective Alternate Hosts of an Emerging Polerovirus in Cotton Landscapes in the Southeastern United States.Viruses · 2022Article
- Effector-mediated plant-virus-vector interactions.The Plant cell · 2022Review
- RNAi-Based Antiviral Innate Immunity in Plants.Viruses · 2022Review
- Atypical molecular features of RNA silencing against the phloem-restricted polerovirus TuYV.Nucleic acids research · 2021Article
- Cotton Leafroll Dwarf Virus US Genomes Comprise Divergent Subpopulations and Harbor Extensive Variability.Viruses · 2021Article
- Comparative Analysis of Biological Characteristics among P0 Proteins from Different Brassica Yellows Virus Genotypes.Biology · 2021Article
- The Ubiquitin Proteasome System as a Double Agent in Plant-Virus Interactions.Plants (Basel, Switzerland) · 2021Review
- Key Amino Acids forFrontiers in microbiology · 2021Article
- Article
- The viral F-box protein P0 induces an ER-derived autophagy degradation pathway for the clearance of membrane-bound AGO1.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Interaction between Brassica yellows virus silencing suppressor P0 and plant SKP1 facilitates stability of P0 in vivo against degradation by proteasome and autophagy pathways.The New phytologist · 2019Article
- A Suppressor Screen for AGO1 Degradation by the Viral F-Box P0 Protein Uncovers a Role for AGO DUF1785 in sRNA Duplex Unwinding.The Plant cell · 2018Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe RNA silencing pathway is an important anti-viral defense mechanism in plants. As a counter defense, some members of the viral family Luteoviridae are able to evade host immunity by encoding the P0 RNA silencing suppressor protein. Here we explored the functional diversity of P0 proteins among eight cotton leafroll dwarf virus (CLRDV) isolates, a virus associated with a worldwide cotton disease known as cotton blue disease (CBD).
methodsCLRDV-infected cotton plants of different varieties were collected from five growing fields in Brazil and their P0 sequences compared to three previously obtained isolates. P0's silencing suppression activities were scored based on transient expression experiments in Nicotiana benthamiana leaves.
resultsHigh sequence diversity was observed among CLRDV P0 proteins, indicating that some isolates found in cotton varieties formerly resistant to CLRDV should be regarded as new genotypes within the species. All tested proteins were able to suppress local and systemic silencing, but with significantly variable degrees. All P0 proteins were able to mediate the decay of ARGONAUTE proteins, a key component of the RNA silencing machinery.
conclusionsThe sequence diversity observed in CLRDV P0s is also reflected in their silencing suppression capabilities. However, the strength of local and systemic silencing suppression was not correlated for some proteins.
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