ArticleBioorganic & medicinal chemistry2015
Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses.
Article in Bioorganic & medicinal chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Article
- Chemo-proteomics reveals dihydrocaffeic acid exhibits anti-inflammation effects via Transaldolase 1 mediated PERK-NF-κB pathway.Cell communication and signaling : CCS · 2025Article
- Dihydrocaffeic Acid-Is It the Less Known but Equally Valuable Phenolic Acid?Biomolecules · 2023Review
- Bio-Based Valorization of Lignin-Derived Phenolic Compounds: A Review.Biomolecules · 2023Review
- Lipase-Catalyzed Synthesis, Antioxidant Activity, Antimicrobial Properties and Molecular Docking Studies of Butyl Dihydrocaffeate.Molecules (Basel, Switzerland) · 2022Article
- Laccases and Tyrosinases in Organic Synthesis.International journal of molecular sciences · 2022Review
- Dendrimeric Structures in the Synthesis of Fine Chemicals.Materials (Basel, Switzerland) · 2021Review
- Engineered tyrosinases with broadened bio-catalysis scope: immobilization using nanocarriers and applications.3 Biotech · 2021Review
- Antiviral Nanomaterials for Designing Mixed Matrix Membranes.Membranes · 2021Review
- Laccase-Catalyzed 1,4-Dioxane-Mediated Synthesis of BelladineInternational journal of molecular sciences · 2021Article
- Advances in Antiviral Material Development.ChemPlusChem · 2020Article
- A Three-Step, Gram-Scale Synthesis of Hydroxytyrosol, Hydroxytyrosol Acetate, and 3,4-Dihydroxyphenylglycol.Molecules (Basel, Switzerland) · 2019Article
- A Polyphenol Rich Extract fromMolecules (Basel, Switzerland) · 2018Article
- Functionalized Tyrosinase-Lignin Nanoparticles as Sustainable Catalysts for the Oxidation of Phenols.Nanomaterials (Basel, Switzerland) · 2018Article
- The Amphibian Antimicrobial Peptide Temporin B InhibitsAntimicrobial agents and chemotherapy · 2018Article
- Differential Redox State Contributes to Sex Disparities in the Response to Influenza Virus Infection in Male and Female Mice.Frontiers in immunology · 2018Article
- Five New Phenolic Compounds with Antioxidant Activities from the Medicinal Insect Blaps rynchopetera.Molecules (Basel, Switzerland) · 2017Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydroxytyrosol and dihydrocaffeoyl catechols with lipophilic properties have been synthesized in high yield using tyrosinase immobilized on multi-walled carbon nanotubes by the Layer-by-Layer technique. All synthesized catechols were evaluated against a large panel of DNA and RNA viruses, including Poliovirus type 1, Echovirus type 9, Herpes simplex virus type 1 (HSV-1), Herpes simplex virus type 2 (HSV-2), Coxsackievirus type B3 (Cox B3), Adenovirus type 2 and type 5 and Cytomegalovirus (CMV). A significant antiviral activity was observed in the inhibition of HSV-1, HSV-2, Cox B3 and CMV. The mechanism of action of the most active dihydrocaffeoyl derivative was investigated against a model of HSV-1 infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.