Evidence map›Paper›PMID 26260151›Full record

ArticleJournal of bone and mineral metabolism2016

Association between vitamin D status and serum parathyroid hormone concentration and calcaneal stiffness in Japanese adolescents: sex differences in susceptibility to vitamin D deficiency.

Naoko Tsugawa, Kazuhiro Uenishi, Hiromi Ishida, Reo Ozaki, Tomoki Takase, Takuya Minekami, Yuri Uchino, Maya Kamao, Toshio Okano

Abstract read
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In one paragraph

Article in Journal of bone and mineral metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

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  10. Insufficiency of B vitamins with its possible clinical implications.Journal of clinical biochemistry and nutrition · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Naoko TsugawaDepartment of Hygienic Sciences, Kobe Pharmaceutical University, Kobe, Japan. tsugawa.naoko@osaka-shoin.ac.jp.
Kazuhiro UenishiLaboratory of Physiological Nutrition, Kagawa Nutrition University, Sakado, Japan.
Hiromi IshidaLaboratory of Administrative Dietetics, Kagawa Nutrition University, Sakado, Japan.
Reo OzakiDepartment of Hygienic Sciences, Kobe Pharmaceutical University, Kobe, Japan.
Tomoki TakaseDepartment of Hygienic Sciences, Kobe Pharmaceutical University, Kobe, Japan.
Takuya MinekamiDepartment of Hygienic Sciences, Kobe Pharmaceutical University, Kobe, Japan.
Yuri UchinoDepartment of Hygienic Sciences, Kobe Pharmaceutical University, Kobe, Japan.
Maya KamaoDepartment of Hygienic Sciences, Kobe Pharmaceutical University, Kobe, Japan.
Toshio OkanoDepartment of Hygienic Sciences, Kobe Pharmaceutical University, Kobe, Japan.
Kobe Pharmaceutical University · JPKagawa Nutrition University · JPOsaka Shoin Women's University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is currently insufficient information on serum 25-hydroxyvitamin D (25OHD) and parathyroid hormone (PTH) concentrations, and bone mineral status in healthy adolescents to allow reference values to be set. This study aimed to provide comparable data on vitamin D status in Japanese adolescents and to assess sex differences in susceptibility to vitamin D insufficiency. Serum 25OHD and PTH concentrations were measured in 1,380 healthy adolescents (aged 12-18 years). Subjects completed a questionnaire on exercise history, diet, and lifestyle factors. Calcaneal stiffness was evaluated by quantitative ultrasound. Serum 25OHD concentrations in boys and girls were 60.8 ± 18.3 and 52.8 ± 17.0 nmol/L, respectively. Approximately 30 % of boys and 47 % of girls had suboptimal 25OHD concentrations (<50 nmol/L). Serum PTH concentration was negatively correlated with serum 25OHD concentration in boys, but negatively correlated with calcium intake rather than serum 25OHD in girls. In contrast, the increment in calcaneal stiffness as a result of elevation of serum 25OHD was higher in girls than in boys. As vitamin D deficiency is common in Japanese adolescents, it was estimated that intakes of ≥12 and ≥14 μg/day vitamin D would be required to reach 25OHD concentrations of 50 nmol/L in boys and girls, respectively. Moreover, the results of the present study indicate that vitamin D deficiency has a greater association with calcaneal stiffness in girls than in boys.

Indexed as

Achilles TendonSex CharacteristicsUltrasonographyVitamin D DeficiencyAdolescentDisease SusceptibilityFemaleHumansMaleParathyroid HormoneVitamin D25-hydroxyvitamin DParathyroid HormoneVitamin D25-Hydroxyvitamin DAdolescentBone mineral densityParathyroid hormoneVitamin D

Identifiers

PMID26260151
OpenAlexW1186065799

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.