SynthesisClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2015
Prevalence of Barrett's Esophagus in Asian Countries: A Systematic Review and Meta-analysis.
Synthesis in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05818072 (The Prevalence, Risk Factors and Optimal Biopsy Protocol of Barrett's Esophagus in Taiwan - A Prospective Randomized Study), which is not on this map. Cited by 45 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Prevalence, Risk Factors and Optimal Biopsy Protocol of Barrett's Esophagus in Taiwan - A Prospective Randomized Study
Who cites it
45 citing papers in PubMed, 7 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- The prevalence of Barrett 's esophagus in Iranian patients with gastrointestinal symptoms: a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Thailand guideline 2020 for medical management of gastroesophageal reflux disease.Journal of gastroenterology and hepatology · 2022Guideline
- Risk Prediction Model for Esophageal Cancer Among General Population: A Systematic Review.Frontiers in public health · 2021Pooled it
- The global prevalence of Barrett's esophagus: A systematic review of the published literature.United European gastroenterology journal · 2020Pooled it
- The relationship between metabolic syndrome and increased risk of Barrett's esophagus: an updated systematic review and meta-analysis.BMC gastroenterology · 2020Pooled it
- Progression from low-grade dysplasia to malignancy in patients with Barrett's esophagus diagnosed by two or more pathologists.World journal of gastroenterology · 2016Pooled it
- Dietary fruit, vegetable, fat, and red and processed meat intakes and Barrett's esophagus risk: a systematic review and meta-analysis.Scientific reports · 2016Pooled it
- Comparison of Invasive Interventions for Halting the Progression of Barrett's Esophagus.Cureus · 2026Review
- Risk factors for barrett's esophagus identified in a large-scale Japanese community cohort study.Scientific reports · 2026Article
- Barrett's esophagus around the world: a systematic review and predictive modeling study.Gastroenterology and hepatology from bed to bench · 2026Review
- Barrett's esophagus: A review.World journal of gastrointestinal pathophysiology · 2025Review
- A YOLO Ensemble Framework for Detection of Barrett's Esophagus Lesions in Endoscopic Images.Diagnostics (Basel, Switzerland) · 2025Article
- Increased Prevalence of Barrett's Esophagus in Taiwan: A Prospective Multicenter Study.Journal of gastroenterology and hepatology · 2025Article
- Age distribution and risk factors for Barrett's esophagus by sex at health check-up settings in Japan.Journal of gastroenterology · 2025Article
- Development of a prediction score for Barrett's esophagus in Japanese health checkup settings.Esophagus : official journal of the Japan Esophageal Society · 2024Article
- Prospect and Challenges of Volatile Organic Compound Breath Testing in Non-Cancer Gastrointestinal Disorders.Biomedicines · 2024Review
- Trends in oesophageal cancer mortality in Montenegro, 1990-2018.European journal of public health · 2024Article
- Investigating the causal relationship of gut microbiota with GERD and BE: a bidirectional mendelian randomization.BMC genomics · 2024Article
- Artificial intelligence system for the detection of Barrett's esophagus.World journal of gastroenterology · 2023Article
- Endoscopic diagnosis and screening of Barrett's esophagus: Inconsistency of diagnostic criteria between Japan and Western countries.DEN open · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
BACKGROUND &
aimsThe prevalence and risk factors of Barrett's esophagus (BE) in Asian countries are unclear. Studies report a wide range of BE prevalence in Asian countries. We conducted a systematic review and meta-analysis to examine the prevalence of BE and its temporal changes and risk factors in Asian countries.
methodsTwo investigators performed independent literature searches by using PubMed and EMBASE databases, and subsequent data abstraction for studies had to meet several set inclusion and exclusion criteria. Pooled BE prevalence was calculated by using a random-effect model. Estimates of relative risk for possible risk or protective factors were also calculated.
resultsA total of 51 studies (N = 453,147), mainly from Eastern Asia, were included. The pooled prevalence of endoscopic BE was 7.8% (95% confidence interval, 5.0-12.1; 23 studies) and of histologically confirmed BE was 1.3% (95% confidence interval, 0.7-2.2; 28 studies). Most of histologic BE (82.1%) was short-segment BE (<3 cm). There was a trend toward an increase in prevalence of BE over time from 1991 to 2014, especially in Eastern Asian countries. Within BE cohorts, pooled prevalence of low-grade dysplasia, high-grade dysplasia, and esophageal adenocarcinoma was 6.9%, 3.0%, and 2.0%, respectively. Reflux symptoms, male sex, hiatus hernia, and smoking were associated with a significantly increased risk of histologic BE in patients with BE compared with patients without BE. However, half of the patients with histologic BE did not have reflux symptoms.
conclusionsBE is not uncommon in Asian countries and seems to share similar risk factors and potential for neoplastic progression to those seen in Western countries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.