Evidence map›Paper›PMID 26259958›Full record

ReviewAlcoholism, clinical and experimental research2015

Guidelines for the Reporting of Treatment Trials for Alcohol Use Disorders.

Katie Witkiewitz, John W Finney, Alex H S Harris, Daniel R Kivlahan, Henry R Kranzler

Abstract readReview
In one paragraph

Review in Alcoholism, clinical and experimental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
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  5. Article
  6. Community characteristics and substance-free activity and service access predict membership in alcohol use disorder risk profiles.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  7. Article
  8. Article
  9. Novel medications for problematic alcohol use.The Journal of clinical investigation · 2024
    Review
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  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katie WitkiewitzDepartment of Psychology, University of New Mexico, Albuquerque, New Mexico.
John W FinneyCenter for Innovation to Implementation, VA Palo Alto Health Care System, Menlo Park, California.
Alex H S HarrisCenter for Innovation to Implementation, VA Palo Alto Health Care System, Menlo Park, California.
Daniel R KivlahanVeterans Health Administration, Washington, District of Columbia.
Henry R KranzlerCenter for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Funding

Precision Medicine and Recovery in a Telehealth Treatment Program for Alcohol Use DisorderR01AA022328 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2013 to 2026
$3.1M
Pharmacogenetic Analysis of Topiramate Treatment of AUDR01AA023192 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI KRANZLER, HENRY RICHARD · 2014 to 2018
$2.7M
2/2 Pharmacogenetic Treatment for AlcoholismR01AA021164 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI KRANZLER, HENRY RICHARD, PETTINATI, HELEN M · 2012 to 2016
$2.1M
NIAAA NIH HHS AA021164NIAAA NIH HHS AA022328NIAAA NIH HHS AA023192NIAAA NIH HHS R01 AA021164NIAAA NIH HHS R01 AA022328NIAAA NIH HHS R01 AA023192
6 · The paper itself

Abstract

backgroundThe primary goals in conducting clinical trials of treatments for alcohol use disorders (AUDs) are to identify efficacious treatments and determine which treatments are most efficacious for which patients. Accurate reporting of study design features and results is imperative to enable readers of research reports to evaluate to what extent a study has achieved these goals. Guidance on quality of clinical trial reporting has evolved substantially over the past 2 decades, primarily through the publication and widespread adoption of the Consolidated Standards of Reporting Trials statement. However, there is room to improve the adoption of those standards in reporting the design and findings of treatment trials for AUD.

methodsThis paper provides a narrative review of guidance on reporting quality in AUD treatment trials.

resultsDespite improvements in the reporting of results of treatment trials for AUD over the past 2 decades, many published reports provide insufficient information on design or methods.

conclusionsThe reporting of alcohol treatment trial design, analysis, and results requires improvement in 4 primary areas: (i) trial registration, (ii) procedures for recruitment and retention, (iii) procedures for randomization and intervention design considerations, and (iv) statistical methods used to assess treatment efficacy. Improvements in these areas and the adoption of reporting standards by authors, reviewers, and editors are critical to an accurate assessment of the reliability and validity of treatment effects. Continued developments in this area are needed to move AUD treatment research forward via systematic reviews and meta-analyses that maximize the utility of completed studies.

Indexed as

Alcohol-Related DisordersGuidelines as TopicHumansRandomized Controlled Trials as TopicResearch ReportAlcohol Clinical TrialsAlcohol Use DisorderCONSORTEligibility CriteriaMultisite Studies

Identifiers

PMID26259958
PMCPMC4558296

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.