Evidence map›Paper›PMID 26259945›Full record

ArticleThe American journal of tropical medicine and hygiene2015

Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network.

Ananias A Escalante, Marcelo U Ferreira, Joseph M Vinetz, Sarah K Volkman, Liwang Cui, Dionicia Gamboa, Donald J Krogstad, Alyssa E Barry, Jane M Carlton, Anna Maria van Eijk and 7 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Imported malaria predominates in near-elimination settings in Southwestern Uganda.medRxiv : the preprint server for health sciences · 2026
    Article
  4. Article
  5. Article
  6. Genetic diversity and haplotype structure of theFrontiers in cellular and infection microbiology · 2025
    Article
  7. IDO1-AhR axis increases T regulatory cells inFrontiers in immunology · 2025
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  8. Article
  9. Parasite epidemiology and control · 2024
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  15. Article
  16. Article
  17. Population structure and genetic connectivity ofFrontiers in epidemiology · 2023
    Article
  18. Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ananias A Escalante
Marcelo U Ferreira
Joseph M Vinetz
Sarah K Volkman
Liwang Cui
Dionicia Gamboa
Donald J Krogstad
Alyssa E Barry
Jane M Carlton
Anna Maria van Eijk
Khageswar Pradhan
Ivo Mueller
Bryan Greenhouse
M Andreina Pacheco
Andres F Vallejo
Socrates Herrera
Ingrid Felger

Funding

Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joaniter Immaculate Nankabirwa · 2010 to 2026
$29.3M
Southeast Asia Malaria Research CenterU19AI089672 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2010 to 2023
$28.9M
Using Next-Generation Genomics to Study Antimalarial Drug Resistance in IndiaU19AI089676 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CARLTON, JANE M · 2010 to 2023
$22.6M
Sugar-feeding behavior of the malaria vector Nyssorhynchus darlingi and development of effective attractive toxic sugar baits (ATSB) to increase intervention success in PeruU19AI089681 · NIAID · YALE UNIVERSITY · PI GAZZINELLI, RICARDO TOSTES · 2010 to 2023
$20.1M
Vector Biology Research and Integrated Vector Management For Malaria ControlU19AI089702 · NIAID · CAUCASECO SCIENTIFIC RESEARCH CENTER · PI HERRERA VALENCIA, SOCRATES · 2010 to 2016
$11.5M
Sequencing and Genomics CoresU19AI089696 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KROGSTAD, DONALD JOHN · 2010 to 2016
$10.6M
TransmissionU19AI089686 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ZIMMERMAN, PETER A. · 2010 to 2016
$9.9M
NIAID NIH HHS U19 AI089672NIAID NIH HHS U19 AI089674NIAID NIH HHS U19 AI089676NIAID NIH HHS U19 AI089681NIAID NIH HHS U19 AI089686NIAID NIH HHS U19 AI089696NIAID NIH HHS U19 AI089702
6 · The paper itself

Abstract

Molecular epidemiology leverages genetic information to study the risk factors that affect the frequency and distribution of malaria cases. This article describes molecular epidemiologic investigations currently being carried out by the International Centers of Excellence for Malaria Research (ICEMR) network in a variety of malaria-endemic settings. First, we discuss various novel approaches to understand malaria incidence and gametocytemia, focusing on Plasmodium falciparum and Plasmodium vivax. Second, we describe and compare different parasite genotyping methods commonly used in malaria epidemiology and population genetics. Finally, we discuss potential applications of molecular epidemiological tools and methods toward malaria control and elimination efforts.

Indexed as

Gene FlowGenetics, PopulationGenotyping TechniquesHumansInternational CooperationMalariaMalaria, FalciparumMalaria, VivaxMolecular EpidemiologyPlasmodiumPlasmodium falciparumPlasmodium vivax

Identifiers

PMID26259945
PMCPMC4574277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.