Evidence map›Paper›PMID 26259934›Full record

ReviewNature reviews. Cardiology2016

Recurrent pericarditis: new and emerging therapeutic options.

Massimo Imazio, George Lazaros, Antonio Brucato, Fiorenzo Gaita

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 76 citations in OpenAlex.

  1. Review
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  15. Post-BMJ case reports · 2021
    Article
  16. Article
  17. Review
  18. The off-label use of anakinra in pediatric systemic autoinflammatory diseases.Therapeutic advances in musculoskeletal disease · 2020
    Review
  19. Article
  20. Radical Pericardiectomy for Pericardial Diseases.Current cardiology reports · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Massimo ImazioCardiology Department, Maria Vittoria Hospital, and Department of Public Health and Pediatrics, University of Torino, Via Luigi Cibrario 72, 10141 Torino, Italy.
George LazarosCardiology Department, University of Athens Medical School, Hippokration General Hospital, 114 Vassilissis Sophias Avenue, Athens 115 27, Greece.
Antonio BrucatoInternal Medicine, Azienda Ospedaliera, Papa Giovanni XXIII, Piazza OMS 1, 24127 Bergamo, Italy.
Fiorenzo GaitaUniversity Division of Cardiology, Department of Medical Science, AOU Città della Salute e della Scienza di Torino, 10126 Torino, Italy.
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITNational and Kapodistrian University of Athens · GROspedale Maria Vittoria · ITOspedale Papa Giovanni XXIII · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent pericarditis is one of the most common and troublesome complications after an episode of pericarditis, and affects 20-50% of patients treated for pericarditis. In most of these patients, the pericarditis remains idiopathic, although an immune-mediated (either autoimmune or autoinflammatory) pathogenesis is often presumed. The mainstay of therapy for recurrences is aspirin or NSAIDs, with the adjunct of colchicine. Corticosteroids are a second-line option to be considered for specific indications, such as connective tissue disease or pregnancy; contraindications or intolerance to aspirin, NSAIDs, and/or colchicine; or insufficient response to these medications. Furthermore, corticosteroids can be added to NSAIDs and colchicine in patients with persistent symptoms. In patients who do not respond adequately to any of these conventional therapies, alternative treatment options include azathioprine, intravenous human immunoglobulins, and anakinra. An improved understanding of how recurrent pericarditis develops after an initiating event is critical to prevent this complication, and further research is needed into the pathogenesis of recurrences. We discuss the aetiology and diagnosis of recurrent pericarditis, and extensively review the treatment options for this condition.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalAntirheumatic AgentsAspirinAzathioprineColchicineGlucocorticoidsHumansImmunoglobulins, IntravenousImmunologic FactorsImmunosuppressive AgentsInterleukin 1 Receptor Antagonist ProteinPericarditisRecurrenceTreatment OutcomeAnti-Inflammatory Agents, Non-SteroidalAntirheumatic AgentsAspirinAzathioprineColchicineGlucocorticoidsImmunoglobulins, IntravenousImmunologic FactorsImmunosuppressive AgentsInterleukin 1 Receptor Antagonist Protein

Identifiers

PMID26259934
OpenAlexW2252467796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.