Evidence map›Paper›PMID 26259720›Full record

ReviewBioengineered2015

Bioengineering for Organ Transplantation: Progress and Challenges.

Ted Welman, Sebastian Michel, Nicholas Segaren, Kumaran Shanmugarajah

Abstract readReview
In one paragraph

Review in Bioengineered, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Bioengineered · 2022
    Article
  5. Article
  6. Article
  7. Review
  8. Current topics in glycemic control by wearable artificial pancreas or bedside artificial pancreas with closed-loop system.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2016
    Review
  9. Stem cell death and survival in heart regeneration and repair.Apoptosis : an international journal on programmed cell death · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ted Welmana Ashford and St Peter's Hospitals NHS Foundation Trust ; Chertsey, Surrey , United Kingdom.
Sebastian Michelb Department of Cardiac Surgery ; Ludwig-Maximilians-Universtät München ; Munich , Germany.
Nicholas Segarenc Department of Plastic Surgery ; Addenbrooke's Hospital ; Cambridge , United Kingdom.
Kumaran Shanmugarajahd Division of Surgery and Cancer; Imperial College London ; London , United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organ transplantation can offer a curative option for patients with end stage organ failure. Unfortunately the treatment is severely limited by the availability of donor organs. Organ bioengineering could provide a solution to the worldwide critical organ shortage. The majority of protocols to date have employed the use of decellularization-recellularization technology of naturally occurring tissues and organs with promising results in heart, lung, liver, pancreas, intestine and kidney engineering. Successful decellularization has provided researchers with suitable scaffolds to attempt cell reseeding. Future work will need to focus on the optimization of organ specific recellularization techniques before organ bioengineering can become clinically translatable. This review will examine the current progress in organ bioengineering and highlight future challenges in the field.

Indexed as

AnimalsBatch Cell Culture TechniquesBioartificial OrgansBiomedical EngineeringHumansOrgan Culture TechniquesTissue EngineeringTissue Scaffoldsbioengineeringdecellularizationorgan transplantationrecellularizationregenerative medicine

Identifiers

PMID26259720
PMCPMC4825836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.