Evidence map›Paper›PMID 26259121›Full record

Observational studyJournal of hypertension2015

Association of anxiety and depression with hypertension control: a US multidisciplinary group practice observational study.

Aaron K Ho, Carolyn T Thorpe, Nancy Pandhi, Mari Palta, Maureen A Smith, Heather M Johnson

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Cultural Approaches to Promote Indigenous Mental Health: Weaving Healthy Families.Journal of ethnic & cultural diversity in social work · 2025
    Article
  7. Review
  8. Observational
  9. Article
  10. Article
  11. Article
  12. La Tunisie medicale · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Impacts of Anxiety and Depression on Clinical Hypertension in Low-Income US Adults.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Aaron K HoaDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin bCenter for Health Equity Research and Promotion, Veterans Affairs Pittsburgh Healthcare System cDepartment of Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania dHealth Innovation Program eDepartment of Family Medicine fDepartment of Population Health Sciences gDepartment of Biostatistics and Medical Informatics hDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Carolyn T Thorpe
Nancy Pandhi
Mari Palta
Maureen A Smith
Heather M Johnson
Johnson & Johnson (United States) · USUniversity of Pittsburgh · USUniversity of Wisconsin–Madison · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Identifying and Addressing Barriers to Hypertension Control in Young AdultsK23HL112907 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI JOHNSON, HEATHER M · 2012 to 2016
$845k
Continuity of Care and the Health of Older AdultsK08AG029527 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI PANDHI, NANCY · 2009 to 2013
$669k
Impact of Rheumatologist Communication Upon Managing Cardiovascular Risk in RAK23AR062381 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI BARTELS, CHRISTIE MICHELS · 2012 to 2015
$423k
NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1TR000427NCRR NIH HHS UL1 RR025011NCRR NIH HHS UL1RR025011NHLBI NIH HHS K23 HL112907NHLBI NIH HHS K23HL112907NIAMS NIH HHS K23 AR062381NIA NIH HHS K08 AG029527NIA NIH HHS K08AG029527
6 · The paper itself

Abstract

objectiveThe presence of a mental health disorder with hypertension is associated with higher cardiovascular disease mortality than hypertension alone. Although earlier detection of hypertension has been demonstrated in patients with anxiety and depression, the relationship of mental health disorders to hypertension control is unknown. Our objective was to evaluate rates and predictors of incident hypertension control among patients with anxiety and/or depression compared with patients without either mental health diagnosis.

methodsA 4-year retrospective analysis included 4362 patients, at least 18 years old, who received primary care in a large academic group practice from 2008 to 2011. Patients met The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure criteria and had a hypertension diagnosis. Kaplan-Meier analysis estimated the probability of achieving control for patients with and without anxiety and/or depression. Cox proportional hazard models were fit to identify predictors of time to control.

resultsOverall, 13% (n = 573) had a baseline diagnosis of anxiety and/or depression. Those with anxiety and/or depression demonstrated more primary care and specialty visits than those without either condition. After adjustment, patients with anxiety and/or depression had faster rates of hypertension control (hazard ratio [HR] 1.22; 1.07-1.39] than patients without either diagnosis. Other associations of faster hypertension control included female gender (HR 1.32; 1.20-1.44), absence of tobacco use (HR 1.17; 1.03-1.33), Medicaid use (HR 1.27; 1.09-1.49), and a higher Adjusted Clinical Group Risk Score (HR 1.13; 1.10-1.17), a measure of healthcare utilization.

conclusionGreater healthcare utilization among patients with anxiety and/or depression may contribute to faster hypertension control.

Indexed as

AdultAgedAnxietyDepressionFemaleGroup PracticeHumansHypertensionIncidenceMaleMiddle AgedPrimary Health CareRetrospective StudiesUnited States

Identifiers

PMID26259121
PMCPMC4690617
OpenAlexW1455439922

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.