Evidence map›Paper›PMID 26259091›Full record

ReviewAlcohol research : current reviews2015

Advances in Diagnosis and Treatment of Fetal Alcohol Spectrum Disorders: From Animal Models to Human Studies.

Nathen J Murawski, Eileen M Moore, Jennifer D Thomas, Edward P Riley

Open access · greenAbstract readReview
In one paragraph

Review in Alcohol research : current reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
23.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.

  1. Meta-Analyses of Externalizing Disorders: Genetics or Prenatal Alcohol Exposure?Alcoholism, clinical and experimental research · 2018
    Pooled it
  2. Trial
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  17. Influence ofInternational journal of environmental research and public health · 2022
    Article
  18. Review of rodent models of attention deficit hyperactivity disorder.Neuroscience and biobehavioral reviews · 2022
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nathen J MurawskiCenter for Behavioral Teratology, San Diego State University, San Diego, California.
Eileen M MooreDepartment of Psychology, San Diego State University, San Diego, California.
Jennifer D ThomasCenter for Behavioral Teratology; Department of Psychology; San Diego State University, San Diego, California.
Edward P RileyCenter for Behavioral Teratology; Department of Psychology; San Diego State University, San Diego, California.
National Postdoctoral Association · US

Funding

Cross-Cultural Assessment of FASDU24AA014811 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY · 2003 to 2026
$13.1M
Fetal Alcohol Effects and Choline InterventionR01AA012446 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI THOMAS, JENNIFER D · 2001 to 2015
$3.8M
Utility of Olfactory Function Measures in Children with Prenatal Alcohol ExposureK99AA022661 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI MOORE, EILEEN MARIE · 2014 to 2015
$189k
NIAAA NIH HHS K99 AA022661NIAAA NIH HHS R01 AA012446NIAAA NIH HHS R01-AA-012446NIAAA NIH HHS U24 AA014811NIAAA NIH HHS U24-AA014811
6 · The paper itself

Abstract

Prenatal alcohol exposure can cause a number of physical, behavioral, cognitive, and neural impairments, collectively known as fetal alcohol spectrum disorders (FASD). This article examines basic research that has been or could be translated into practical applications for the diagnosis or treatment of FASD. Diagnosing FASD continues to be a challenge, but advances are being made at both basic science and clinical levels. These include identification of biomarkers, recognition of subtle facial characteristics of exposure, and examination of the relation between face, brain, and behavior. Basic research also is pointing toward potential new interventions for FASD involving pharmacotherapies, nutritional therapies, and exercise interventions. Although researchers have assessed the majority of these treatments in animal models of FASD, a limited number of recent clinical studies exist. An assessment of this literature suggests that targeted interventions can improve some impairments resulting from developmental alcohol exposure. However, combining interventions may prove more efficacious. Ultimately, advances in basic and clinical sciences may translate to clinical care, improving both diagnosis and treatment.

Indexed as

Disease Models, AnimalAnimalsFetal Alcohol Spectrum DisordersHumans

Identifiers

PMID26259091
PMCPMC4476607
OpenAlexW1135715668

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.