ArticleNature chemical biology2015
A fungal monooxygenase-derived jasmonate attenuates host innate immunity.
Article in Nature chemical biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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Who cites it
74 citing papers in PubMed, 159 citations in OpenAlex.
- The 11-hydroxy-jasmonic acid pathway expands jasmonate catabolic repertoire for stress-specific hormone attenuation in Arabidopsis.Nature communications · 2026Article
- Metabolite-mediated plant immunity: From traditional defenders to artificial elicitors.Journal of integrative plant biology · 2026Review
- Ancient origins of alkaloid biosynthesis in medicinal clubmosses.bioRxiv : the preprint server for biology · 2026Article
- The plant endophytic fungus Cyanodermella asteris produces the phytohormone jasmonic acid.Fungal biology and biotechnology · 2026Article
- Characteristics and genome analysis of Enterobacter bugandensis C5-7 reveal its utilization value of maize growth promotion in saline-alkali land.World journal of microbiology & biotechnology · 2026Article
- Deciphering Molecular Pathways ofMicroorganisms · 2026Article
- MeJA-Induced Plant Disease Resistance: A Review.Plants (Basel, Switzerland) · 2026Review
- The phenol-2-monooxygenase FgPhm1 regulates DON synthesis, pathogenicity and environmental stress response inVirulence · 2025Article
- Metabolomics navigates natural variation in pathogen-induced secondary metabolism across soybean cultivar populations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A glyoxal-specific aldehyde signaling axis in Pseudomonas aeruginosa that influences quorum sensing and infection.Nature communications · 2025Article
- Salicylic acid and jasmonic acid in plant immunity.Horticulture research · 2025Article
- Rice JASMONIC ACID OXIDASES control resting jasmonate metabolism to promote growth and repress basal immune responses.Plant physiology · 2025Article
- A catalogue of virulence strategies mediated by phytopathogenic effectors.Fundamental research · 2025Review
- Impact of Nutrient Stress on Plant Disease Resistance.International journal of molecular sciences · 2025Review
- Sugars, Lipids and More: New Insights Into Plant Carbon Sources During Plant-Microbe Interactions.Plant, cell & environment · 2025Review
- Phosphite inhibitsFrontiers in microbiology · 2025Article
- Chemical biology research in RIKEN NPDepo aimed at agricultural applications.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025Review
- Comparative analyses of RNA-seq and phytohormone data of sweetpotatoes inoculated with Dickeya dadantii causing bacterial stem and root rot of sweetpotato.BMC plant biology · 2024Article
- Empirical evidence for metabolic drift in plant and algal lipid biosynthesis pathways.Frontiers in plant science · 2024Review
- Plant-Fungi Interactions: Where It Goes?Biology · 2023Review
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Distinct modifications fine-tune the activity of jasmonic acid (JA) in regulating plant growth and immunity. Hydroxylated JA (12OH-JA) promotes flower and tuber development but prevents induction of JA signaling, plant defense or both. However, biosynthesis of 12OH-JA has remained elusive. We report here an antibiotic biosynthesis monooxygenase (Abm) that converts endogenous free JA into 12OH-JA in the model rice blast fungus Magnaporthe oryzae. Such fungal 12OH-JA is secreted during host penetration and helps evade the defense response. Loss of Abm in M. oryzae led to accumulation of methyl JA (MeJA), which induces host defense and blocks invasive growth. Exogenously added 12OH-JA markedly attenuated abmΔ-induced immunity in rice. Notably, Abm itself is secreted after invasion and most likely converts plant JA into 12OH-JA to facilitate host colonization. This study sheds light on the chemical arms race during plant-pathogen interaction, reveals Abm as an antifungal target and outlines a synthetic strategy for transformation of a versatile small-molecule phytohormone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.