Evidence map›Paper›PMID 26258567›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2015

Implementation and Operational Research: Strengthening HIV Test Access and Treatment Uptake Study (Project STATUS): A Randomized Trial of HIV Testing and Counseling Interventions.

A D McNaghten, Allison Schilsky Mneimneh, Thato Farirai, Nafuna Wamai, Marylad Ntiro, Jennifer Sabatier, Nondumiso Makhunga-Ramfolo, Salli Mwanasalli, Anna Awor, Jan Moore and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

A D McNaghten*Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA; †Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, GA; ‡Centers for Disease Control and Prevention, Pretoria, South Africa; §Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Entebbe, Uganda; ‖Ministry of Health and Social Welfare, Dar es Salaam, Tanzania; ¶University Research Co., LLC, Pretoria, South Africa; and #Centers for Disease Control and Prevention, Dar es Salaam, Tanzania.
Allison Schilsky Mneimneh
Thato Farirai
Nafuna Wamai
Marylad Ntiro
Jennifer Sabatier
Nondumiso Makhunga-Ramfolo
Salli Mwanasalli
Anna Awor
Jan Moore
Project STATUS Study Team
Centers for Disease Control and Prevention · UG

Funding

Intramural CDC HHS CC999999PEPFAR
6 · The paper itself

Abstract

objectiveTo determine which of 3 HIV testing and counseling (HTC) models in outpatient departments (OPDs) increases HIV testing and entry of newly identified HIV-infected patients into care.

designRandomized trial of HTC interventions.

methodsThirty-six OPDs in South Africa, Tanzania, and Uganda were randomly assigned to 3 different HTC models: (A) health care providers referred eligible patients (aged 18-49, not tested in the past year, not known HIV positive) to on-site voluntary counseling and testing for HTC offered and provided by voluntary counseling and testing counselors after clinical consultation; (B) health care providers offered and provided HTC to eligible patients during clinical consultation; and (C) nurse or lay counselors offered and provided HTC to eligible patients before clinical consultation. Data were collected from October 2011 to September 2012. We describe testing eligibility and acceptance, HIV prevalence, and referral and entry into care. Chi-square analyses were conducted to examine differences by model.

resultsOf 79,910 patients, 45% were age eligible and 16,099 (45%) age eligibles were tested. Ten percent tested HIV positive. Significant differences were found in percent tested by model. The proportion of age eligible patients tested by Project STATUS was highest for model C (54.1%, 95% confidence interval [CI]: 42.4 to 65.9), followed by model A (41.7%, 95% CI: 30.7 to 52.8), and then model B (33.9%, 95% CI: 25.7 to 42.1). Of the 1596 newly identified HIV positive patients, 94% were referred to care (96.1% in model A, 94.7% in model B, and 94.9% in model C), and 58% entered on-site care (74.4% in model A, 54.8% in model B, and 55.6% in model C) with no significant differences in referrals or care entry by model.

conclusionsModel C resulted in the highest proportion of all age-eligible patients receiving a test. Although 94% of STATUS patients with a positive test result were referred to care, only 58% entered care. We found no differences in patients entering care by HTC model. Routine HTC in OPDs is acceptable to patients and effective for identifying HIV-infected persons, but additional efforts are needed to increase entry to care.

Indexed as

AdolescentAdultAmbulatory CareAnti-Retroviral AgentsCounselingFemaleHIV InfectionsHumansMaleMiddle AgedPatient Acceptance of Health CareSouth AfricaTanzaniaUgandaYoung AdultAnti-Retroviral Agents

Identifiers

PMID26258567
PMCPMC4714543
OpenAlexW2654930999

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.