Evidence map›Paper›PMID 26258153›Full record

ArticleJournal of addictive behaviors, therapy & rehabilitation

Managing Opioid Use Disorder During and After Acute Hospitalization: A Case-Based Review Clarifying Methadone Regulation for Acute Care Settings.

Amanda Noska, Aron Mohan, Sarah Wakeman, Josiah Rich, Amy Boutwell

Abstract read
In one paragraph

Article in Journal of addictive behaviors, therapy & rehabilitation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Making Sense: Treating Patients with Opioid Use Disorder through the Lens of Game Theory.Journal of community hospital internal medicine perspectives · 2024
    Article
  5. Concurrent opioid and alcohol withdrawal management.The mental health clinician · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amanda NoskaBrown University and Warren Alpert Medical School, Providence, RI, USA ; Lifespan Corporation, Rhode Island Hospital and The Miriam Hospital, Providence, RI, USA.
Aron MohanBrown University and Warren Alpert Medical School, Providence, RI, USA.
Sarah WakemanMassachusetts General Hospital, Department of Medicine, Boston, MA, USA ; Harvard Medical School, Boston, MA, USA.
Josiah RichBrown University and Warren Alpert Medical School, Providence, RI, USA ; Lifespan Corporation, Rhode Island Hospital and The Miriam Hospital, Providence, RI, USA.
Amy BoutwellMassachusetts General Hospital, Department of Medicine, Boston, MA, USA ; Harvard Medical School, Boston, MA, USA ; Collaborative Healthcare Strategies, Lexington, MA, USA.
Brown University · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
Midcareer Investigator Award in Patient Oriented ResearchK24DA022112 · NIDA · MIRIAM HOSPITAL · PI RICH, JOSIAH D · 2008 to 2017
$1.7M
NIAID NIH HHS P30 AI042853NIDA NIH HHS K24 DA022112
6 · The paper itself

Abstract

objectiveTreatment with an opioid agonist such as methadone or buprenorphine is the standard of care for opioid use disorder. Persons with opioid use disorder are frequently hospitalized, and may be undertreated due to provider misinformation regarding the legality of prescribing methadone for inpatients. Using a case-based review, this article aims to describe effective management of active opioid withdrawal and ongoing opioid use disorder using methadone or buprenorphine among acutely ill, hospitalized patients.

methodsWe reviewed pertinent medical and legal literature and consulted with national legal experts regarding methadone for opioid withdrawal and opioid maintenance therapy in hospitalized, general medical and surgical patients, and describe a real-life example of successful implementation of inpatient methadone for these purposes.

resultsPatients with opioid use disorders can be effectively and legally initiated on methadone maintenance therapy or buprenorphine during an inpatient hospitalization by clinical providers and successfully transitioned to an outpatient methadone maintenance or buprenorphine clinic after discharge for ongoing treatment.

conclusionsInpatient methadone or buprenorphine prescribing is safe and evidence-based, and can be used to effectively treat opioid withdrawal and also serves as a bridge to outpatient treatment of opioid use disorders.

Identifiers

PMID26258153
PMCPMC4527170
OpenAlexW2299172150

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.