Evidence map›Paper›PMID 26257987›Full record

ArticleSurgical neurology international2015

Atypical pleomorphic neoplasms of the pineal gland: Case report and review of the literature.

M Praver, R D'Amico, C Arraez, B E Zacharia, H Varma, J E Goldman, J N Bruce, P Canoll

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Surgical neurology international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

M PraverDepartment of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.
R D'AmicoDepartment of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.
C ArraezDepartment of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.
B E ZachariaDepartment of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.
H VarmaPathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
J E GoldmanPathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
J N BruceDepartment of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.
P CanollDepartment of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.
Neurological Surgery · USColumbia University Irving Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPineal region tumors are rare and diverse. Among them exist reports of pleomorphic xanthroastrocytoma (PXA) and pleomorphic granular cell astrocytoma (PGCA) of the pineal gland. These related tumors are remarkably similar sharing pleomorphic histologic features with only minor immunohistochemical and ultrastructural differences. CASE DESCRIPTION: We present a case of a 42-year old right-handed woman presented with a longstanding history of migraine headaches which had worsened over the two months leading up to her hospitalization. MRI revealed a 1.7 × 1.3 × 1.6 cm intensely enhancing lesion originating in the pineal gland. The tumor closely resembled PGCA but did not strictly fit the diagnostic requirements of either PGCA or PXA.

conclusionThe present case highlights the exotic nature of pineal region tumors with pleomorphic cell histology. Given the diverse range of tumors encountered in the pineal region, pathological confirmation is mandatory. Favorable clinical outcomes demonstrate that surgical resection alone can yield excellent long-term results for tumors falling within the spectrum of pleomorphic lesions of the pineal gland.

Indexed as

Pineal glandpleomorphic granular cell astrocytomapleomorphic xanthoastrocytoma

Identifiers

PMID26257987
PMCPMC4524004
OpenAlexW2415600744

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.