Evidence map›Paper›PMID 26257927›Full record

ReviewJournal of advanced research2015

New era for management of chronic hepatitis C virus using direct antiviral agents: A review.

Tamer Elbaz, Mohamed El-Kassas, Gamal Esmat

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of advanced research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Direct-acting antivirals for chronic hepatitis C.The Cochrane database of systematic reviews · 2017
    Pooled it
  2. Direct-acting antivirals for chronic hepatitis C.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. A significant upsurge of body mass index in patients with chronic hepatitis C successfully treated with direct-acting antiviral regimens.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tamer ElbazEndemic Medicine and Hepatogastroenterology Department, Faculty of Medicine, Cairo University, Egypt.
Mohamed El-KassasHepatology Department, National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt.
Gamal EsmatEndemic Medicine and Hepatogastroenterology Department, Faculty of Medicine, Cairo University, Egypt.
Cairo University · EGNational Water Research Center · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pegylated interferon regimen has long been the lone effective management of chronic hepatitis C with modest response. The first appearance of protease inhibitors included boceprevir and telaprevir. However, their efficacy was limited to genotype 1. Recently, direct antiviral agents opened the gate for a real effective management of HCV, certainly after FDA approval of some compounds that further paved the way for the appearance of enormous potent direct antiviral agents that may achieve successful eradication of HCV.

Indexed as

Direct antiviral agents (DAA)HCVPolymerase inhibitorsProtease inhibitors

Identifiers

PMID26257927
PMCPMC4522579
OpenAlexW1965742280

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.