Evidence map›Paper›PMID 26257861›Full record

ArticleMedChemComm2015

Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin.

Nikhil R Madadi, Hongliang Zong, Amit Ketkar, Chen Zheng, Narsimha R Penthala, Venumadhav Janganati, Shobanbabu Bommagani, Robert L Eoff, Monica L Guzman, Peter A Crooks

Open access · greenAbstract read
In one paragraph

Article in MedChemComm, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Natural and nature-inspired stilbenoids as antiviral agents.European journal of medicinal chemistry · 2020
    Review
  7. Article
  8. HybridInternational journal of molecular sciences · 2019
    Review
  9. A novel tetrazole analogue of resveratrol is a potent anticancer agent.Bioorganic & medicinal chemistry letters · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nikhil R MadadiDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Hongliang ZongDivision of Hematology and Medical Oncology, Department of Medicine, Weill Medical College of Cornell University, New York, NY.
Amit KetkarDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Chen ZhengDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Narsimha R PenthalaDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Venumadhav JanganatiDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Shobanbabu BommaganiDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Robert L EoffDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Monica L GuzmanDivision of Hematology and Medical Oncology, Department of Medicine, Weill Medical College of Cornell University, New York, NY.
Peter A CrooksDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
University of Arkansas for Medical Sciences · USCornell University · US

Funding

Selection of Novel Therapies to Ablate Chemoresistant Myeloid Leukemia Stem CellDP2OD007399 · OD · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUZMAN, MONICA L · 2010 to 2010
$2.5M
Development of Small Molecule Radiation SensitizersR01CA140409 · NCI · VANDERBILT UNIVERSITY · PI FREEMAN, MICHAEL L., KONJETI, SEKHAR RAJA · 2010 to 2014
$1.7M
Translesion DNA polymerase kappa activity in gliomasR01CA183895 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI EOFF, ROBERT L · 2014 to 2018
$1.5M
NCI NIH HHS R01 CA140409NCI NIH HHS R01 CA183895NIH HHS DP2 OD007399
6 · The paper itself

Abstract

A series of novel diarylacrylonitrile and

Identifiers

PMID26257861
PMCPMC4527554
OpenAlexW1996658532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.