ArticleThe journal of venomous animals and toxins including tropical diseases2015
Neuroactive compounds obtained from arthropod venoms as new therapeutic platforms for the treatment of neurological disorders.
Article in The journal of venomous animals and toxins including tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Therapeutic Potential of Scorpion Venom Proteins: Innovations in Cancer Treatment and Future Directions.Current drug targets · 2026Review
- Harnessing the potency of scorpion venom-derived proteins: applications in cancer therapy.Bioresources and bioprocessing · 2024Review
- Article
- A new class of peptides from wasp venom: a pathway to antiepileptic/neuroprotective drugs.Brain communications · 2023Article
- Spider Neurotoxins as Modulators of NMDA Receptor Signaling.Neuromolecular medicine · 2022Review
- Discovery of Leptulipin, a New Anticancer Protein from theIranian Scorpion,Molecules (Basel, Switzerland) · 2022Article
- Bee venom acupuncture therapy ameliorates neuroinflammatory alterations in a pilocarpine-induced epilepticus model.Metabolic brain disease · 2021Article
- Venoms as an adjunctive therapy for Parkinson's disease: where are we now and where are we going?Future science OA · 2020Review
- Fraternine, a Novel Wasp Peptide, Protects against Motor Impairments in 6-OHDA Model of Parkinsonism.Toxins · 2020Article
- Carbohydrate Metabolic Compensation Coupled to High Tolerance to Oxidative Stress in Ticks.Scientific reports · 2019Article
- Intravitreal injection of the synthetic peptide LyeTx I b, derived from a spider toxin, into the rabbit eye is safe and prevents neovascularization in a chorio-allantoic membrane model.The journal of venomous animals and toxins including tropical diseases · 2018Article
- Disease Modifying Effects of the Spider Toxin Parawixin2 in the Experimental Epilepsy Model.Toxins · 2017Article
- Anticonvulsant Effects of Fractions Isolated from Dinoponera quadriceps (Kempt) Ant Venom (Formicidae: Ponerinae).Toxins · 2016Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The impact of neurological disorders in society is growing with alarming estimations for an incidence increase in the next decades. These disorders are generally chronic and can affect individuals early during productive life, imposing real limitations on the performance of their social roles. Patients can have their independence, autonomy, freedom, self-image, and self-confidence affected. In spite of their availability, drugs for the treatment of these disorders are commonly associated with side effects, which can vary in frequency and severity. Currently, no effective cure is known. Nowadays, the biopharmaceutical research community widely recognizes arthropod venoms as a rich source of bioactive compounds, providing a plethora of possibilities for the discovery of new neuroactive compounds, opening up novel and attractive opportunities in this field. Several identified molecules with a neuropharmacological profile can act in the central nervous system on different neuronal targets, rendering them useful tools for the study of neurological disorders. In this context, this review aims to describe the current main compounds extracted from arthropod venoms for the treatment of five major existing neurological disorders: stroke, Alzheimer's disease, epilepsy, Parkinson's disease, and pathological anxiety.
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Registered trials
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