Evidence map›Paper›PMID 26256941›Full record

GuidelineBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2015

Indications for Autologous and Allogeneic Hematopoietic Cell Transplantation: Guidelines from the American Society for Blood and Marrow Transplantation.

Navneet S Majhail, Stephanie H Farnia, Paul A Carpenter, Richard E Champlin, Stephen Crawford, David I Marks, James L Omel, Paul J Orchard, Jeanne Palmer, Wael Saber and 5 more

Abstract readGuideline
In one paragraph

Guideline in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
160citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

160 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Trial
  5. An evidence-based stress management intervention for allogeneic hematopoietic stem cell transplant caregivers: development, feasibility and acceptability.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Trial
  6. Article
  7. Article
  8. Longitudinal assessment and predictors of subjective taste change after hematopoietic cell transplantation (HCT).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Exploring facilitators and barriers to daily chlorhexidine gluconate bathing in adult patients undergoing hematopoietic stem cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article

100 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Navneet S MajhailBlood & Marrow Transplant Program, Cleveland Clinic, Cleveland, OH.
Stephanie H FarniaPayer Policy, National Marrow Donor Program, Minneapolis, MN.
Paul A CarpenterClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Richard E ChamplinDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX.
Stephen CrawfordCigna LifeSource Transplant Network, Pittsburgh, PA.
David I MarksAdult BMT Unit, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
James L OmelGrand Island, NE.
Paul J OrchardDepartment of Pediatrics, University of Minnesota, Minneapolis, MN.
Jeanne PalmerDivision of Hematology/Oncology, Mayo Clinic, Phoenix, AZ.
Wael SaberDivision of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI.
Bipin N SavaniDivision of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN.
Paul A VeysBone Marrow Transplantation Unit, Great Ormond Street Hospital for Children, London, UK.
Christopher N BredesonMalignant Hematology & Stem Cell Transplantation, The Ottawa Hospital, Ottawa, ON.
Sergio A Giralt *Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Charles F LeMaistre *Sarah Cannon, Nashville, TN.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
NCI NIH HHS P30 CA016672NCI NIH HHS U24 CA076518
6 · The paper itself

Abstract

Approximately 20,000 hematopoietic cell transplantation (HCT) procedures are performed in the United States annually. With advances in transplantation technology and supportive care practices, HCT has become safer, and patient survival continues to improve over time. Indications for HCT continue to evolve as research refines the role for HCT in established indications and identifies emerging indications where HCT may be beneficial. The American Society for Blood and Marrow Transplantation (ASBMT) established a multiple-stakeholder task force consisting of transplant experts, payer representatives, and a patient advocate to provide guidance on "routine" indications for HCT. This white paper presents the recommendations from the task force. Indications for HCT were categorized as follows: (1) Standard of care, where indication for HCT is well defined and supported by evidence; (2) Standard of care, clinical evidence available, where large clinical trials and observational studies are not available but HCT has been shown to be effective therapy; (3) Standard of care, rare indication, for rare diseases where HCT has demonstrated effectiveness but large clinical trials and observational studies are not feasible; (4) Developmental, for diseases where preclinical and/or early phase clinical studies show HCT to be a promising treatment option; and (5) Not generally recommended, where available evidence does not support the routine use of HCT. The ASBMT will periodically review these guidelines and will update them as new evidence becomes available.

Indexed as

Bone Marrow TransplantationHematopoietic Stem Cell TransplantationAdultAge FactorsChildClinical Trials as TopicHematologic NeoplasmsHumansRare DiseasesSocieties, MedicalStandard of CareTransplantation, AutologousTransplantation, HomologousUnited StatesAllogeneic transplantationAutologous transplantationClinical trialsHematopoietic cell transplantationIndicationsRoutine careStandard of care

Identifiers

PMID26256941
PMCPMC4830270

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.