Evidence map›Paper›PMID 26256293›Full record

ReviewInfluenza and other respiratory viruses2015

The Global Influenza Initiative recommendations for the vaccination of pregnant women against seasonal influenza.

Alejandro E Macias, Alexander R Precioso, Ann R Falsey, Global Influenza Initiative

Open access · goldAbstract readReview
In one paragraph

Review in Influenza and other respiratory viruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
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  10. The fetal origins of mental illness.American journal of obstetrics and gynecology · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Alejandro E MaciasDepartment of Medicine, University of Guanajuato, Leon, Mexico.
Alexander R PreciosoDivision of Clinical Trials and Pharmacovigilance, Instituto Butantan, São Paulo, Brazil.
Ann R FalseyDepartment of Medicine, Rochester General Hospital and University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Global Influenza Initiative
Instituto Butantan · BRRochester General Hospital · USUniversidad de Guanajuato · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a heavy disease burden due to seasonal influenza in pregnant women, their fetuses, and their newborns. The main aim of this study was to review and analyze current evidence on safety, immunogenicity, and clinical benefits of the inactivated influenza vaccine (IIV) in pregnant women. Current evidence shows that in pregnant women, the seasonal and pandemic IIVs are safe and well tolerated. After vaccination, pregnant women have protective concentrations of anti-influenza antibodies, conferring immunogenicity in newborns. The best evidence, to date, suggests that influenza vaccination confers clinical benefits in both pregnant women and their newborns. Vaccination with either the seasonal or pandemic vaccine has been shown to be cost-effective in pregnancy. There are scarce data from randomized clinical trials; fortunately, new phase 3 clinical trials are under way. In the Northern and Southern Hemispheres, data suggest that the greatest clinical benefit for infants occurs if the IIV is administered within the first weeks of availability of the vaccine, at the beginning of the influenza season, regardless of the pregnancy trimester. The optimal timing to vaccinate pregnant women who live in tropical regions is unclear. Based on evaluation of the evidence, the Global Influenza Initiative (GII) recommends that to prevent seasonal influenza morbidity and mortality in infants and their mothers, all pregnant women, regardless of trimester, should be vaccinated with the IIV. For countries where vaccination against influenza is starting or expanding, the GII recommends that pregnant women have the highest priority.

Indexed as

Global HealthAdultFemaleHumansInfant, NewbornInfluenza, HumanInfluenza VaccinesPandemicsPregnancyPregnancy Complications, InfectiousPregnant PeopleSeasonsVaccines, InactivatedInfluenza VaccinesVaccines, InactivatedGlobal Influenza Initiativeinfluenzapregnancypregnant womenrecommendationsvaccination

Identifiers

PMID26256293
PMCPMC4549100
OpenAlexW2102475580

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.