Evidence map›Paper›PMID 26256117›Full record

ArticleHealth services research2016

Financial Strain and Medication Adherence among Diabetes Patients in an Integrated Health Care Delivery System: The Diabetes Study of Northern California (DISTANCE).

Courtney R Lyles, Hilary K Seligman, Melissa M Parker, Howard H Moffet, Nancy Adler, Dean Schillinger, John D Piette, Andrew J Karter

Abstract read
In one paragraph

Article in Health services research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Knowledge of Interpreter Rights and Medication Delays in Diabetes Care.Journal of immigrant and minority health · 2026
    Article
  4. Article
  5. Not obtaining a medication the first time it is prescribed: primary non-adherence to cardiovascular pharmacotherapy.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Food Insecurity Among Veterans: Resources to Screen and Intervene.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2020
    Article
  14. Physician Perceptions of Step Therapy Prescribing Requirements.Journal of managed care & specialty pharmacy · 2019
    Article
  15. Observational
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Courtney R LylesUniversity of California San Francisco, 1001 Potrero Ave, San Francisco, CA.
Hilary K SeligmanDivision of General Internal Medicine at SFGH, UCSF Center for Vulnerable Populations, San Francisco, CA.
Melissa M ParkerKaiser Permanente Northern California Division of Research, Oakland, CA.
Howard H MoffetKaiser Permanente Northern California Division of Research, Oakland, CA.
Nancy AdlerUCSF Departments of Psychiatry and Pediatrics, San Francisco, CA.
Dean SchillingerDivision of General Internal Medicine at SFGH, UCSF Center for Vulnerable Populations, San Francisco, CA.
John D PietteSchools of Public Health and Medicine, VA Ann Arbor Center for Clinical Management Research, University of Michigan, Ann Arbor, MI.
Andrew J KarterKaiser Permanente Northern California Division of Research, Oakland, CA.

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GERMAN, MICHAEL S · 2003 to 2019
$21.8M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Ethnic Disparities in Diabetes ComplicationsR01DK065664 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI KARTER, ANDREW JOHN · 2004 to 2008
$3.3M
Diabetes and Aging in a Multi-Ethnic PopulationR01DK081796 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI HUANG, ELBERT S., KARTER, ANDREW JOHN · 2009 to 2013
$2.9M
Educational Disparities in Diabetes ComplicationsR01HD046113 · NICHD · KAISER FOUNDATION RESEARCH INSTITUTE · PI KARTER, ANDREW JOHN · 2003 to 2006
$1.6M
Medication Adherence and Social Disparities in DiabetesR01DK080726 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI KARTER, ANDREW JOHN · 2009 to 2012
$1.5M
Engaging Diverse Patients in Using an Online Patient PortalR00HS022408 · AHRQ · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LYLES, COURTNEY REES · 2015 to 2017
$740k
Engaging Diverse Patients in Using an Online Patient PortalK99HS022408 · AHRQ · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LYLES, COURTNEY REES · 2013 to 2014
$311k
AHRQ HHS K99 HS022408AHRQ HHS R00 HS022408NICHD NIH HHS R01 HD046113NICHD NIH HHS R01 HD46113NIDDK NIH HHS P30 DK063720NIDDK NIH HHS P30 DK092924NIDDK NIH HHS P30 DK092926NIDDK NIH HHS P30 DK098722NIDDK NIH HHS R01 DK065664NIDDK NIH HHS R01 DK080726NIDDK NIH HHS R01 DK081796
6 · The paper itself

Abstract

objectiveTo examine self-reported financial strain in relation to pharmacy utilization adherence data. DATA SOURCES/STUDY

settingSurvey, administrative, and electronic medical data from Kaiser Permanente Northern California. STUDY

designRetrospective cohort design (2006, n = 7,773). DATA COLLECTION/EXTRACTION

methodsWe compared survey self-reports of general and medication-specific financial strain to three adherence outcomes from pharmacy records, specifying adjusted generalized linear regression models. PRINCIPAL

findingsEight percent and 9 percent reported general and medication-specific financial strain. In adjusted models, general strain was significantly associated with primary nonadherence (RR = 1.37; 95 percent CI: 1.04-1.81) and refilling late (RR = 1.34; 95 percent CI: 1.07-1.66); and medication-specific strain was associated with primary nonadherence (RR = 1.42, 95 percent CI: 1.09-1.84).

conclusionsSimple, minimally intrusive questions could be used to identify patients at risk of poor adherence due to financial barriers.

Indexed as

Drug MonitoringSelf ReportAdolescentAdultAntihypertensive AgentsCaliforniaDelivery of Health Care, IntegratedDiabetes MellitusDrug UtilizationFemaleHumansHypoglycemic AgentsHypolipidemic AgentsMaleMiddle AgedRetrospective StudiesAntihypertensive AgentsHypoglycemic AgentsHypolipidemic AgentsAdherencecost of carediabetesmanaged care

Identifiers

PMID26256117
PMCPMC4799896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.